用于无标签生物传感的聚合环谐振器

2015 1st Workshop on Nanotechnology in Instrumentation and Measurement (NANOFIM) Pub Date : 2015-07-01 DOI:10.1109/NANOFIM.2015.8425361

I. A. Grimaldi, G. Persichetti, G. Testa, R. Bernini

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引用次数: 0

摘要

我们开发了一种用于无标记生物传感的生物光子环谐振器。我们首先研究了一种优化方法来提高基于Su-8的环形谐振器的光学性能。利用质量因子对超薄苏-8底层的效果进行评价。由于衬底和环形材料之间的聚合物亲和性得到了改善，从而获得了约20%的改进。该生物光子器件与聚二甲基硅氧烷(PDMS)微流控通道集成，用于生物分子检测。实验结果表明，环形谐振器固定在Su-8表面后，能够检测牛血清白蛋白(BSA)的生物分子。

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Polymeric Ring Resonators for Label-Free Biosensing

We developed a biophotonic ring resonators for label-free biosensing. We first study an optimization approach for improving the optical performance of Su-8 based ring resonator. The effects of an ultrathin Su-8 under-layer are evaluated in terms of quality factor. An improvement of about 20% is obtained, as a consequence of the improved polymeric affinity between the substrate and the ring material. The biophotonic device is, than, integrated with polydimethylsiloxane (PDMS) microfluidic channel for biomolecule detection. The experimental results indicated that the ring resonators are able to detect the biomolecules of bovine serum albumin (BSA) after their immobilization on the Su-8 surface.

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2015 1st Workshop on Nanotechnology in Instrumentation and Measurement (NANOFIM)

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