一种提高低剂量CT扫描图像质量的模型

Francesca Chircop, C. J. Debono, P. Bezzina, F. Zarb
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摘要

计算机断层扫描(CT)在医学成像诊断中使用,因为它们通过利用x射线提供详细的人体横断面图像。作为医学诊断的一部分,x射线辐射会给患者带来健康风险,因此专家们尽可能选择低剂量的辐射。根据欧洲指令,医疗用途的电离辐射剂量应保持在合理可行的最低水平(ALARA)。虽然从健康的角度来看,减少辐射是有益的,但这会影响图像的质量,因为图像中的噪声会增加,从而降低放射科医生对诊断的信心。文献中的各种低剂量CT (LDCT)图像去噪策略都试图解决这一冲突。然而,目前的模型面临着过于平滑的结果和丢失详细信息等问题。因此,去噪后的LDCT图像质量仍然是一个重要的问题。本工作中提出的模型使用了针对该问题进行修改和训练的深度学习技术。结果表明,在图像质量方面,最佳模型的峰值信噪比(PSNR)为19.5 dB,结构相似指数(SSIM)为0.7153,均方根误差(RMSE)为43.34。执行所需操作的平均时间为4843.80。此外,还进行了不同剂量水平下的试验,以检验最佳模型的稳健性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Model to Improve the Quality of Low-dose CT Scan Images
Computed Tomography (CT) scans are used during medical imaging diagnosis as they provide detailed cross-sectional images of the human body by making use of X-rays. X-ray radiation as part of medical diagnosis poses health risks to patients leading experts to opt for low doses of radiation when possible. In accordance with European Directives, ionising radiation doses for medical purposes are to be kept as low as reasonably achievable (ALARA). While reduced radiation is beneficial from a health perspective, this impacts the quality of the images as the noise in the images increases, reducing the radiologist’s confidence in diagnosis. Various low-dose CT (LDCT) image denoising strategies available in the literature attempt to solve this conflict. However, current models face problems like over-smoothed results and lose detailed information. Consequently, the quality of LDCT images after denoising is still an important problem. The models presented in this work use deep learning techniques that are modified and trained for this problem. The results show that the best model in terms of image quality achieved a peak signal to noise ratio (PSNR) of 19.5 dB, a structural similarity index measure (SSIM) of 0.7153 and a root mean square error (RMSE) of 43.34. It performed the required operations in an average time of 4843.80s. Furthermore, tests at different dose levels were done to test the robustness of the best performing models.
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