SARS-CoV-2感染与人体危险因素、肺部效应和药物作用的系统发育分析

Ilman Ahnaf, L. Mauro, Rafa Ahmed Yesvi, M. Naeem, Abu Syed Md., Anan Sabit Ibtisam, Haque Tazwan
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引用次数: 1

摘要

SARS-CoV-2是一种和谐的病毒,其极强的传播能力与蝙蝠冠状病毒有关,它通过三个主要过程传播:吸入SARS-CoV-2感染者的飞沫,与患者接触,以及被病毒污染的表面和材料。因此,蝙蝠冠状病毒与引起大流行的病毒SARS-CoV-2非常相似,蝙蝠经常被认为是可能的主要宿主,尽管在传播手段方面还没有确定中间媒介。刺突糖蛋白在ACE2受体和受体结合域的帮助下,在穿透的情况下起着重要的作用。在人体内,SARS-CoV-2通过侵入宿主细胞的核酸,攻击一个细胞,一个接一个地侵入整个人体;因此,考虑到免疫能力,感染病例分为有症状和无症状。患有心血管疾病或糖尿病的患者通常使用ACE2进行治疗;因此,感染的可能性可能很高。鉴于SARS-CoV-2先感染血液,然后感染肺部,为了避免高度复杂的影响,改进抗原可以更好。目前,没有疫苗接种,也没有准确的治愈和治疗方法。从病毒学、免疫学和分子生物学等方面对新冠病毒进行了解释和分析。为了更好地理解这一概念,在此列入了几个有关的数字。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
SARS-CoV-2 infection and phylogenetic analysis with the risk factors in human body alongside the pulmonary effects and medication
Related the extremely transmittable abilities of SARS-CoV-2,a harmonious virus to the bat CoV, gets transmitted by three principal processes-- the inhalation of droplets from the SARS-CoV-2 infected person, contacting to the person, and by the surfaces and materials defiled with the virus. Whereupon bat Coronavirus is mostly like the pandemic causing virus SARS-CoV-2, bats are often deliberated and figured out as a possible primary host although no intermediate has not been defined yet in the wherewithal of transmission. The Spike Glycoprotein plays an important role in the case of penetration with the assistance of the ACE2 receptor and the Receptor Binding Domain. In the human body, infiltrating the nucleic acid into host cells, SARS-CoV-2 attacks one cell and one by one into the whole human body; therefore, infected cases are found symptomatic and asymptomatic considering the immune power. Patients with cardiovascular disease or diabetes proceed with their treatment with ACE2 often; therefore, there might be a high chance of getting infected. Whereas the SARS-CoV-2 infects the blood and then lungs, Antigens improvement can be better in order to avoid high-complicated effects. Currently, no vaccination or no accurate cure and treatment has not been defined. An explanation with analysis on SARS-CoV-2 has been performed from the aspect of virology, immunology and molecular biology. Several relevant figures have been included hereby in order to a better understanding of the very concept.
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