骨和骨髓转移的放射学检测。

H Jacobsson, H Göransson
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引用次数: 14

摘要

骨显像是诊断骨转移瘤的主要方法。这项调查是敏感的,但解释必须在知识,它也是非特异性的情况下进行。尽管如此,通常还是可以做出正确的诊断。第一手的补充调查,在可疑的科学发现之后,是放射线照相。在大多数情况下,这足以诊断。当放射学异常不能充分解释时,通常是因为放射学检查阴性,必须使用更敏感的方式。计算机断层扫描提供了更高的灵敏度和特异性,主要用于这一目的。通过这种方式,提高了对比度分辨率,减少了由模糊组织和复杂解剖结构引起的问题。由于骨转移通过活跃的骨髓转移,另一种补充研究是骨髓显像。由于肝脏和脾脏的干扰活动使活跃的骨髓的很大一部分变得模糊,而且病变必须达到一定的大小才能变得明显,因此它的作用受到限制。磁共振成像能很好地显示肿瘤在软组织中的延伸。由于高成本和有限的可用性,它仍然主要用于术前转移的定位。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Radiological detection of bone and bone marrow metastases.

Bone scintigraphy is the primary method for the diagnosis of skeletal metastases. This investigation is sensitive, but the interpretation must be performed in the knowledge that it is also nonspecific. Despite this, a correct diagnosis can usually be achieved. The first-hand supplementary investigation, after a doubtful scintigraphic finding, is radiography. In most cases this is sufficient for a diagnosis. When a scintigraphic abnormality cannot be adequately explained, usually because of a negative radiographic examination, a more sensitive modality must be used. Computerized tomography offers increased sensitivity and specificity, and is primarily used for this purpose. In this way contrast resolution is increased and problems caused by obscuring tissue and complicated anatomy are reduced. Since bone metastases migrate via the active bone marrow an alternative supplementary investigation is bone marrow scintigraphy. Its usefulness is restricted by disturbing activity, from the liver and the spleen, which obscures a significant part of the active marrow, and by the fact that a lesion must be of a certain size to become apparent. Magnetic resonance imaging yields excellent images of the extension of a tumor in soft tissue. Owing to high costs and restricted availability it is still mainly used for preoperative location of metastases.

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