{"title":"一例通过乙羟胆酸(UDCA)治疗，肝功能异常得到改善的肝结节中毒","authors":"文子 齋藤, 真史 高野, 俊治 海瀬, 康文 内海, 直彦 郡司, 良一 石幡, 篤志 入澤, 弘正 大平","doi":"10.11405/NISSHOSHI.107.632","DOIUrl":null,"url":null,"abstract":": A 38-year-old man was admitted to our hospital with a diagnosis of pulmonary sarcoidosis accompanied with elevated biliary enzyme levels. Various imaging modalities, and percutaneous liver biopsy confirmed the diagnosis of hepatic sarcoidosis. Abnormalities of biliary enzymes improved after the administration of ursodeoxycholic acid (UDCA). In this case, the mechanism of pharmacologic action was considered to be the glucocorticoid-like effect of UDCA. UDCA might be a therapeutic option for hepatic sarcoidosis without general symptoms.","PeriodicalId":341053,"journal":{"name":"The Japanese journal of gastro-enterology","volume":"34 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2010-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":"{\"title\":\"ウルソデオキシコール酸(UDCA)治療で肝機能異常の改善を認めた肝サルコイドーシスの1例\",\"authors\":\"文子 齋藤, 真史 高野, 俊治 海瀬, 康文 内海, 直彦 郡司, 良一 石幡, 篤志 入澤, 弘正 大平\",\"doi\":\"10.11405/NISSHOSHI.107.632\",\"DOIUrl\":null,\"url\":null,\"abstract\":\": A 38-year-old man was admitted to our hospital with a diagnosis of pulmonary sarcoidosis accompanied with elevated biliary enzyme levels. Various imaging modalities, and percutaneous liver biopsy confirmed the diagnosis of hepatic sarcoidosis. Abnormalities of biliary enzymes improved after the administration of ursodeoxycholic acid (UDCA). In this case, the mechanism of pharmacologic action was considered to be the glucocorticoid-like effect of UDCA. UDCA might be a therapeutic option for hepatic sarcoidosis without general symptoms.\",\"PeriodicalId\":341053,\"journal\":{\"name\":\"The Japanese journal of gastro-enterology\",\"volume\":\"34 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2010-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"3\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The Japanese journal of gastro-enterology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.11405/NISSHOSHI.107.632\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Japanese journal of gastro-enterology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.11405/NISSHOSHI.107.632","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
: A 38-year-old man was admitted to our hospital with a diagnosis of pulmonary sarcoidosis accompanied with elevated biliary enzyme levels. Various imaging modalities, and percutaneous liver biopsy confirmed the diagnosis of hepatic sarcoidosis. Abnormalities of biliary enzymes improved after the administration of ursodeoxycholic acid (UDCA). In this case, the mechanism of pharmacologic action was considered to be the glucocorticoid-like effect of UDCA. UDCA might be a therapeutic option for hepatic sarcoidosis without general symptoms.
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