局部面部几何区域的判别统计分析

Misae Nakatsu, R. Kimura, X. Han, Yenwei Chen
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引用次数: 2

摘要

日本列岛居民主要包括三种人口;阿伊努人(Ainu)、日本大陆人(Mainland Japanese)和琉球人(Ryukyuan),这些人可以通过全基因组单核苷酸多态性(SNP)数据推断,并以通用碱基序列为特征。另一方面,人类面部形态变异的遗传关联近年来成为一个越来越活跃的研究领域,其目的是定量分析基因基与一类面部形态变异之间可能存在的关系测度。本研究试图探讨日本大陆人与琉球人共同面部形态变异的区别表型特征;在这两个群体之间的表型特征的差异被期望推断不同的基因碱基序列。为了探索面部表型特征,我们提出了一个三维面部图像相邻几何区域的局部统计分析框架。其中,首先选取基于fisher线性判别分析的可分辨值较高的曲面点作为判别坐标向量,并将其聚类成局部几何群进行形态分析;将提取的局部表型特征用于两个群体的鉴定,取得了与全局表型特征相当或更好的性能,这表明局部形态表型与基因之间存在关联分析的可能性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Discriminant statistical analysis of local facial geometrical regions
The residences of Japanese Archipelago mainly include the three human populations; the Ainu, the Mainland Japanese and the Ryukyuan, which can be inferred by genome-wide single-nucleotide polymorphism (SNP) data and characterized by generic base sequences. In the other hand, the genetic association of human facial morphological variation recently becomes a more and more active research field, which aims to quantitatively analyze the possible relation measure between the gene base and a kind offacial morphological variations. This study attempts to explore the discriminated phenotype features of the common facial morphological variations between the Mainland Japanese and the Ryukyuan; the difference of phenotype features between these two populations is prospected to infer different gene base sequences. In order to explore the facial phenotype features, we propose a framework of local statistical analysis for adjacent geometrical regions of 3D facial images. Therein, we firstly select the surface points with higher distinguishable values based fisher linear discriminate analysis as discriminated coordinate vectors, and further cluster them into local geometrical groups for morphological analysis. The extracted local phenotype features are applied for identification of two populations, and achieve the comparable or better performances than the global phenotype feature, which manifests the possibility for association analysis between local morphological phenotype and the genes.
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