{"title":"多元偏态混合模型:荧光活化细胞分选数据的应用","authors":"Kui Wang, S. Ng, G. McLachlan","doi":"10.1109/DICTA.2009.88","DOIUrl":null,"url":null,"abstract":"In many applied problems in the context of pattern recognition, the data often involve highly asymmetric observations. Normal mixture models tend to overfit when additional components are included to capture the skewness of the data. Increased number of pseudo-components could lead to difficulties and inefficiencies in computations. Also, the contours of the fitted mixture components may be distorted. In this paper, we propose to adopt mixtures of multivariate skew t distributions to handle highly asymmetric data. The EM algorithm is used to compute the maximum likelihood estimates of model parameters. The method is illustrated using a flurorescence-activated cell sorting data.","PeriodicalId":277395,"journal":{"name":"2009 Digital Image Computing: Techniques and Applications","volume":"1 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2009-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"60","resultStr":"{\"title\":\"Multivariate Skew t Mixture Models: Applications to Fluorescence-Activated Cell Sorting Data\",\"authors\":\"Kui Wang, S. Ng, G. McLachlan\",\"doi\":\"10.1109/DICTA.2009.88\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"In many applied problems in the context of pattern recognition, the data often involve highly asymmetric observations. Normal mixture models tend to overfit when additional components are included to capture the skewness of the data. Increased number of pseudo-components could lead to difficulties and inefficiencies in computations. Also, the contours of the fitted mixture components may be distorted. In this paper, we propose to adopt mixtures of multivariate skew t distributions to handle highly asymmetric data. The EM algorithm is used to compute the maximum likelihood estimates of model parameters. The method is illustrated using a flurorescence-activated cell sorting data.\",\"PeriodicalId\":277395,\"journal\":{\"name\":\"2009 Digital Image Computing: Techniques and Applications\",\"volume\":\"1 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2009-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"60\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"2009 Digital Image Computing: Techniques and Applications\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/DICTA.2009.88\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"2009 Digital Image Computing: Techniques and Applications","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/DICTA.2009.88","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Multivariate Skew t Mixture Models: Applications to Fluorescence-Activated Cell Sorting Data
In many applied problems in the context of pattern recognition, the data often involve highly asymmetric observations. Normal mixture models tend to overfit when additional components are included to capture the skewness of the data. Increased number of pseudo-components could lead to difficulties and inefficiencies in computations. Also, the contours of the fitted mixture components may be distorted. In this paper, we propose to adopt mixtures of multivariate skew t distributions to handle highly asymmetric data. The EM algorithm is used to compute the maximum likelihood estimates of model parameters. The method is illustrated using a flurorescence-activated cell sorting data.