头颈部癌症的单一机构经验:阿卜杜勒阿齐兹国王大学

R. Al-Wassia, Nisreen Awad, Rahaf A. Al Odaini, S. Alkhayyat, Atlal M. Abusanad, Hani Almarzouki, M. Attar, Talal A. Al Khatib, C. Constantinescu
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引用次数: 0

摘要

本研究旨在评估2011年我院实施调强放疗的头颈癌患者局部-区域控制性和总生存期,以及调强放疗的临床获益。回顾性分析2007 - 2014年117例患者的资料。累积生存率和疾病控制率采用Kaplan-Meier产品极限精算法计算。通过logistic回归检验比较调强放疗和三维适形放疗的局部区域控制率和生存率。中位随访12个月后,53例(51%)接受根治性放疗的患者无疾病,43例(42%)有疾病,7例(7%)未知。在此期间,31名(26%)患者死于该疾病。通过对两年随访的精算估计,本研究发现通过转换治疗方式可显著提高生存率。基准测试保证我们的结果可与国际最佳临床实践相媲美。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Head and Neck Cancer a Single Institution Experience: King Abdulaziz University
The purpose of this study is to assess the loco-regional control and overall survival in head and neck cancer patients, as well as evaluate the clinical benefit of intensity-modulated radiotherapy implemented in 2011 at our Hospital. Data of 117 patients between 2007 and 2014 was reviewed retrospectively. Cumulative survival and disease control rates were calculated by Kaplan-Meier product-limit actuarial method. Loco-regional control and survival rates for intensity modulated and three-dimensional conformal radiotherapy were compared by a logistic regression test. After a median follow-up of 12 months, 53 (51%) patients who underwent radical radiotherapy were free of disease, 43 (42%) with disease, and seven (7%) unknown. During this time, 31 (26%) patients died from the disease. Using actuarial estimates for the two-year follow-up, this study found that significant gains in survival were obtained by switching treatment modalities. The benchmarking gives reassurance that our results are comparable to the best clinical practices internationally.
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