[The "shen" reaction to trauma--an experimental study].

An experimental study using adult Kunming male mice was designed to observe the Shen reaction to trauma (bone fracture and burn). It was shown that the mice testes of the experimental groups were degenerated and the spermatogenesis disturbed. Under the electron microscope, the granules reduction, pyknosis, vesicular degeneration in the plasma of gonadotrophs and hemorrhage were found. It was revealed that the pathological changes of shen by trauma were mainly attacked on the adenohypophysis-gonadal axis. According to the results of this experimental study, the shen in the hypothesis of "trauma hurts shen" should be related to testes and ovaries (gonadal organs).