{"title":"[评估生物活性物质前庭保护作用的新方法的充分性]。","authors":"N N Karkishchenko, N A Dimitriadi","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>The effects of some neuropsychotropic agents on changes in pain sensitivity in albino male rats under the action of complex accelerations were investigated. It was found that administration of drugs with the antimotion-sickness activity--scopolamine, phenamine, phenibut prevented the development of analgesia with the opiate component, the use of low-effective and non-effective with respect to suppression of vestibulo-vegetative disturbances agents--diazepam, ephedrine, haloperidol failed to exert such an effect.</p>","PeriodicalId":12237,"journal":{"name":"Farmakologiia i toksikologiia","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"1991-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[The adequacy of a new method for assessing the vestibular protective effect of biologically active substances].\",\"authors\":\"N N Karkishchenko, N A Dimitriadi\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The effects of some neuropsychotropic agents on changes in pain sensitivity in albino male rats under the action of complex accelerations were investigated. It was found that administration of drugs with the antimotion-sickness activity--scopolamine, phenamine, phenibut prevented the development of analgesia with the opiate component, the use of low-effective and non-effective with respect to suppression of vestibulo-vegetative disturbances agents--diazepam, ephedrine, haloperidol failed to exert such an effect.</p>\",\"PeriodicalId\":12237,\"journal\":{\"name\":\"Farmakologiia i toksikologiia\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1991-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Farmakologiia i toksikologiia\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Farmakologiia i toksikologiia","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
[The adequacy of a new method for assessing the vestibular protective effect of biologically active substances].
The effects of some neuropsychotropic agents on changes in pain sensitivity in albino male rats under the action of complex accelerations were investigated. It was found that administration of drugs with the antimotion-sickness activity--scopolamine, phenamine, phenibut prevented the development of analgesia with the opiate component, the use of low-effective and non-effective with respect to suppression of vestibulo-vegetative disturbances agents--diazepam, ephedrine, haloperidol failed to exert such an effect.
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