María del Carmen Franco Mora, Dr. Bertin Dembele, N. Pérez, R. J. Rodríguez
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Differences were identified between the use of conventional treatment with Silver Sulfadiazine and Lysate Platelet, as well as determining the final outcome of both treatments, in the Plastic Surgery and Cosmetology Service, of the General Clinical-Surgical Hospital \"Dr. Juan Bruno Zayas Alfonso\" of Santiago de Cuba, Cuba in the period from February 2013 to February 2014. Percentages and totals were calculated as a summary measure for qualitative variables for statistical analysis of the data. For quantitative variables, the calculation of the average and the standard deviation was performed. The female sex prevailed at ages 18 to 45, with the lower limbs highlighting as the most affected region, in both treatment groups. The application of lysate platelet favored healing and epithelialization in a shorter time than conventional treatment with silver sulfadiazine, with minimal adverse events, without complications, achieving a better quality of the final scar and excellent satisfaction level perceived by the burnt patient.","PeriodicalId":446681,"journal":{"name":"EAS Journal of Medicine and Surgery","volume":"1 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2022-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Allogenic Lysate Platelet on Deep Second Degree Burns\",\"authors\":\"María del Carmen Franco Mora, Dr. Bertin Dembele, N. Pérez, R. J. Rodríguez\",\"doi\":\"10.36349/easjms.2022.v04i07.002\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Despite the decline in burns incidence and mortality in recent years, its management remains complex. Surface burns usually receive conservative treatment due to their re-epithelizing potential. Regenerative therapies with platelet concentrate are used as physiological reservoirs of growth factors and proteins, capable of accelerating tissue regeneration. A quasi-experimental study was conducted, with two groups of 30 patients to determine the clinical effect of Lysate Platelet on tissue regeneration in patients with deep dermal burns. Differences were identified between the use of conventional treatment with Silver Sulfadiazine and Lysate Platelet, as well as determining the final outcome of both treatments, in the Plastic Surgery and Cosmetology Service, of the General Clinical-Surgical Hospital \\\"Dr. Juan Bruno Zayas Alfonso\\\" of Santiago de Cuba, Cuba in the period from February 2013 to February 2014. Percentages and totals were calculated as a summary measure for qualitative variables for statistical analysis of the data. For quantitative variables, the calculation of the average and the standard deviation was performed. The female sex prevailed at ages 18 to 45, with the lower limbs highlighting as the most affected region, in both treatment groups. 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引用次数: 0
摘要
尽管近年来烧伤的发病率和死亡率有所下降,但其管理仍然很复杂。由于表面烧伤具有再生上皮的潜力,通常接受保守治疗。血小板浓缩物的再生疗法被用作生长因子和蛋白质的生理储库,能够加速组织再生。通过准实验研究,两组30例患者,确定Lysate血小板对皮肤深部烧伤患者组织再生的临床效果。在2013年2月至2014年2月期间,在古巴圣地亚哥的综合临床外科医院" Juan Bruno Zayas Alfonso博士"的整形外科和美容服务处,确定了使用磺胺嘧啶银和裂解血小板的常规治疗之间的差异,并确定了两种治疗的最终结果。计算百分比和总数作为对数据进行统计分析的定性变量的汇总度量。对于定量变量,计算平均值和标准差。在两个治疗组中,18 - 45岁女性居多,下肢突出为最受影响的区域。与传统的磺胺嘧啶银治疗相比,裂解液血小板的应用有利于在更短的时间内愈合和上皮化,不良事件最少,无并发症,最终疤痕质量更好,烧伤患者满意度高。
Allogenic Lysate Platelet on Deep Second Degree Burns
Despite the decline in burns incidence and mortality in recent years, its management remains complex. Surface burns usually receive conservative treatment due to their re-epithelizing potential. Regenerative therapies with platelet concentrate are used as physiological reservoirs of growth factors and proteins, capable of accelerating tissue regeneration. A quasi-experimental study was conducted, with two groups of 30 patients to determine the clinical effect of Lysate Platelet on tissue regeneration in patients with deep dermal burns. Differences were identified between the use of conventional treatment with Silver Sulfadiazine and Lysate Platelet, as well as determining the final outcome of both treatments, in the Plastic Surgery and Cosmetology Service, of the General Clinical-Surgical Hospital "Dr. Juan Bruno Zayas Alfonso" of Santiago de Cuba, Cuba in the period from February 2013 to February 2014. Percentages and totals were calculated as a summary measure for qualitative variables for statistical analysis of the data. For quantitative variables, the calculation of the average and the standard deviation was performed. The female sex prevailed at ages 18 to 45, with the lower limbs highlighting as the most affected region, in both treatment groups. The application of lysate platelet favored healing and epithelialization in a shorter time than conventional treatment with silver sulfadiazine, with minimal adverse events, without complications, achieving a better quality of the final scar and excellent satisfaction level perceived by the burnt patient.