基于微波介电特性的皮肤癌分期检测

Cemanur Aydinalp, Sulayman Joof, T. Yilmaz
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引用次数: 1

摘要

近30年来,生物组织间介电特性的内在差异引起了人们的广泛关注。开放式同轴探头具有无损测量和宽带测量的特点,是一种很有前途的介电性能测量方法。这种方法的进步将改善医疗行业的诊断和治疗过程。本研究的目的不仅是确定皮肤肿瘤,而且是确定癌症分期开放式同轴探头。这将有助于快速、廉价地诊断皮肤癌。为此,我们使用Altair FEKO仿真软件,模拟了一个2.2mm直径的市售开放式同轴探头,对三层乳腺皮肤组织和15种不同体积的肿瘤进行了模拟。在500mhz ~ 2GHz范围内对各配置的s参数进行了仿真。基于模拟s参数的结果表明,在1.5GHz频段,第一阶段与健康组织的s参数差异为11.46%。同样,第二阶段和第三阶段之间的差异约为39.48%。皮肤癌在第三阶段被认为是至关重要的,因此,在介电特性之间以及在探针终止于第二阶段和第三阶段肿瘤组织时的s参数响应之间存在明显差异,将有助于早期皮肤癌的检测。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Microwave Dielectric Property Based Stage Detection of Skin Cancer
Inherent discrepancy of dielectric properties between biological tissues has drawn considerable interest for the last 30 years. Open-ended coaxial probe is one of the promising methods to measure dielectric properties due to the non-destructive and broadband measurement characteristics. The advances in this method will improve the diagnosis and treatment processes in the medical industry. The aim of this study is not only to determine skin tumors but also to identify the cancer stages with open-ended coaxial probes. This will aid rapid an inexpensive diagnosis of skin cancer. To this end, we simulated a 2.2mm diameter open-ended coaxial probe, which is commercially available, with three-layered breast skin tissue and tumors with fifteen different volumes using Altair FEKO simulation software. The S-parameters of each configuration is simulated in the range of 500 MHz to 2GHz. Based on the simulated S-parameters, the results indicate that the first stage and healthy tissue shows a difference of 11.46 % at 1.5GHz. Similarly, there is a difference of about 39.48 % between the second and third stage. Skin cancer is considered critical at the third stage, therefore having a distinctive difference between dielectric properties and thus between the S-parameter response when the probe is terminated with second and the third stage tumor tissue will help in the detection of early stage skin cancer.
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