脂联素基因多态性对复合饮食强迫症患者有氧运动后超重和肥胖个体脂联素含量变化的影响

Comprehensive Health Care Pub Date : 2022-12-30 DOI:10.37362/jch.v6i3.993

Ocd, Muriyati, Asnidar, Stikes Panrita Husada Bulukumba

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摘要

背景:印尼肥胖研究小组调查了超过6000人获得几乎所有省份和肥胖率与身体质量指数(BMI) > 30公斤/ m²在男性为9.16%,女性11.02%。肥胖与脂联素和胰岛素抵抗有关，甚至从很小的时候就开始了。Wiecek(2012)比较了肥胖青少年和正常青少年的脂联素、脂质和胰岛素原水平。从这些研究中，我们知道肥胖青少年的脂联素比正常体重的青少年低50%。目的:探讨脂联素基因多态性在超重个体和肥胖患者有氧运动后脂联素含量变化中的作用。方法:采用实验前设计精确准实验研究设计和一组前后试验设计。研究对象是36名体重超标的女性。结果:有氧运动6周或18次后，脂联素水平与TT基因型差异的man Whitney检验结果差异显著，p值为0.001;GT基因型差异显著，p值为0.038;Spearman相关检验结果为0.301，表明脂联素水平与脂联素基因之间的相关性不显著。spearmen相关值为0.074，说明正相关方向与相关强度很弱，说明有氧运动6周或18次后脂联素水平升高，而有氧运动6周或18次后脂联素水平与脂联素基因的变化无关。结论:有氧运动联合OCD饮食后，GT和TT基因型的脂联素水平显著升高，但有氧运动6周或18次后脂联素水平与脂联素基因变化无关。

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The Role Of Adiponectin Gene Polymorphism On The Change Of Adiponectin Content In Individuals Overweight And Obesity After Aerobic Exercise In Combination Diet OCD

Background: The Indonesian obesity study group examined more than 6000 people from almost all provinces and obtained obesity rates with a body mass index (BMI)> 30 kg / m² in men at 9.16% and women 11.02%. Obesity has been known to be associated with Adiponectin and insulin resistance even from an early age. Wiecek (2012) compared adiponectin, lipid and proinsulin levels between obese and normal adolescents. From these studies, it is known that obese adolescents have adiponectin up to 50% lower compared to teens with normal weight. Aim: To Find Out The Role Of Adiponecttin Gene Polymorphism On The Change Of Adiponextin Content In Overweight Individual And Obesity After Aerobic Exercise In Dicd Ocd Combination. Methods: The research method used is pre-experimental design precisely quasi-experimental research design with one group pre-post test design. The research subjects were 36 women with more than normal body weight. Results: man Whitney test results differed significantly between adiponectin levels with variations in the TT genotype with a p-value of 0.001 and GT with a p-value of 0.038 after doing aerobic exercise for 6 weeks or 18 times of exercise, but the Spearman correlation test obtained a sig value of 0.301 which showed that the correlation was not significant between adiponectin levels and adiponectin genes. The spearmen correlation value of 0.074 indicates that the direction of the positive correlation with the strength of the correlation is very weak meaning that there is an increase in adiponectin levels after aerobic exercise for 6 weeks or 18 times of exercise but adiponectin levels are not related to variations in the adiponectin gene after aerobic exercise for 6 weeks or 18 practice times.. Conclusion: There was a significant increase in adiponectin levels in the GT and TT genotypes after aerobic exercise combined with the OCD diet, but adiponectin levels were not related to variations in the adiponectin gene after aerobic exercise for 6 weeks or 18 times.

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Comprehensive Health Care

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