抗逆转录病毒治疗和艾滋病毒检测需求:来自赞比亚的证据

Nicholas L. Wilson
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引用次数: 22

摘要

本文研究了抗逆转录病毒治疗(ART)对艾滋病毒检测需求的影响以及ART诱导检测对危险性行为需求的影响。我提供了一个不确定性下的性行为决策模型,并使用赞比亚在引入抗逆转录病毒治疗之前和之后的艾滋病毒检测决策的全国代表性调查数据来估计模型的结构参数。实证结果表明,尽管引入抗逆转录病毒治疗似乎使艾滋病毒检测率提高了50%以上,但抗逆转录病毒治疗的分配过程可能限制了抗逆转录病毒治疗诱导检测的预防效益。仿真结果表明,在保持ART供应不变的情况下消除这种预防效率低下,将使ART诱导检测的预防效果提高4倍以上。更一般地说,分析表明,现有的研究,检查“普遍”测试或准实验测试程序低估了标准的自愿咨询和测试程序的功效。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Antiretroviral Therapy and Demand for HIV Testing: Evidence from Zambia
This paper examines the effects of antiretroviral therapy (ART) on demand for HIV testing and of ART-induced testing on demand for risky sexual behavior. I provide a model of sexual behavior decision-making under uncertainty and estimate the structural parameters of the model using nationally representative survey data from Zambia on HIV testing decisions before and after the introduction of ART. The empirical results indicate that although the introduction of ART appears to have increased HIV testing rates by upwards of 50 percent, the ART allocation process may have limited the prevention benefit of ART-induced testing. Simulation results show that eliminating this prevention inefficiency while holding the supply of ART constant would increase the prevention impact of ART-induced testing more than four-fold. More generally, the analysis indicates that existing studies which examine "universal" testing or quasi-experimental testing programs understate the efficacy of standard voluntary counseling and testing programs.
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