Serdar Özdemir, Barış Alper, Hamide Alp, Gökhan Aksel, Fatih Doğanay
{"title":"Karbon Monoksit Zehirlenmesi ve Kardiyak Fonksiyonun Sekelleri","authors":"Serdar Özdemir, Barış Alper, Hamide Alp, Gökhan Aksel, Fatih Doğanay","doi":"10.38175/phnx.1031828","DOIUrl":null,"url":null,"abstract":"Carbon monoxide binds to hemoglobin and shifts the oxyhemoglobin curve to the left, preventing oxygen from being released into the tissues. Thus, it can cause chemical anemia. Elevated levels of cardiac markers such as troponin may be seen when myocardial damage occurs. Electrocardiographic or echocardiographic changes can be monitored. To explain this damage in the myocardium, the toxic effect of carbon monoxide binding to myoglobin is also mentioned in addition to the oxidative stress of carboxyhemoglobin. Carbon monoxide-bound myoglobin is not capable of delivering sufficient oxygen to the myocardium.","PeriodicalId":134281,"journal":{"name":"Phoenix Medical Journal","volume":"37 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2022-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Phoenix Medical Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.38175/phnx.1031828","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Karbon Monoksit Zehirlenmesi ve Kardiyak Fonksiyonun Sekelleri
Carbon monoxide binds to hemoglobin and shifts the oxyhemoglobin curve to the left, preventing oxygen from being released into the tissues. Thus, it can cause chemical anemia. Elevated levels of cardiac markers such as troponin may be seen when myocardial damage occurs. Electrocardiographic or echocardiographic changes can be monitored. To explain this damage in the myocardium, the toxic effect of carbon monoxide binding to myoglobin is also mentioned in addition to the oxidative stress of carboxyhemoglobin. Carbon monoxide-bound myoglobin is not capable of delivering sufficient oxygen to the myocardium.