Serdar Özdemir, Barış Alper, Hamide Alp, Gökhan Aksel, Fatih Doğanay
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引用次数: 0

摘要

一氧化碳与血红蛋白结合,使氧合血红蛋白曲线向左移动,阻止氧气释放到组织中。因此,它可以引起化学性贫血。心肌损伤发生时,心肌标志物如肌钙蛋白水平升高。可以监测心电图或超声心动图的变化。为了解释心肌的这种损伤,除了碳氧血红蛋白的氧化应激外,还提到了一氧化碳与肌红蛋白结合的毒性作用。与一氧化碳结合的肌红蛋白不能向心肌输送足够的氧气。
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Karbon Monoksit Zehirlenmesi ve Kardiyak Fonksiyonun Sekelleri
Carbon monoxide binds to hemoglobin and shifts the oxyhemoglobin curve to the left, preventing oxygen from being released into the tissues. Thus, it can cause chemical anemia. Elevated levels of cardiac markers such as troponin may be seen when myocardial damage occurs. Electrocardiographic or echocardiographic changes can be monitored. To explain this damage in the myocardium, the toxic effect of carbon monoxide binding to myoglobin is also mentioned in addition to the oxidative stress of carboxyhemoglobin. Carbon monoxide-bound myoglobin is not capable of delivering sufficient oxygen to the myocardium.
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