家庭关系验证的快速DNA性能结果

Christopher Miles
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摘要

国土安全部(DHS)科学技术局(S&T)与其他联邦伙伴合作,开发了快速DNA技术,以满足国土安全部核实家庭关系索赔的要求,以减少欺诈和加快合法移民。AABB认可的实验室每年为国土安全部处理数十万项移民关系测试。AABB关系测试小组委员会为这些测试和关系测试实验室的认证制定标准。但是,将采集试剂盒运送到海外并协调DNA采集可能会导致这些测试需要数周到数月的时间来处理,并需要返回结果。快速DNA使用微流体技术将价值百万美元的洁净室DNA处理过程简化为一个独立的、集成的、自动化的桌面系统,在一个封闭的、不干涉的系统中,在90分钟内处理5到7个DNA样本。快速DNA是由国土安全部的外勤人员和特工操作的。它的大小和一台激光打印机差不多,只要能更换打印机墨盒,任何人都可以在办公室操作。它也加固了军事要求,并可以在危险的野外环境中运行发电机电源。安装只需要15分钟。由于“快速DNA”项目取得了成功,可以准确地核实家庭关系,国土安全部确定了更多的需求,以打击沿美国边境的人口贩运,并在发生重大或大规模伤亡事件后使家庭团聚。本报告将讨论国土安全部对家庭关系验证、AABB标准、快速DNA性能和现场测试结果的需求。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Rapid DNA Performance Results on Family Relationship Verification
The Department of Homeland Security (DHS) Science and Technology Directorate (S&T), working with other Federal partners, developed Rapid DNA technology to meet a DHS requirement to verify family relationship claims to reduce fraud and expedite legal immigration. Several hundred thousand immigration relationship tests are processed annually for DHS by AABB accredited laboratories. The AABB Relationship Testing Subcommittee sets the standards for those tests and accreditation of relationship testing laboratories. But, shipping of the collection kits overseas and coordinating DNA collection can cause these tests to take weeks to months to process and results to be returned. Rapid DNA uses microfluidics technology to reduce the million-dollar clean-room DNA processes down to a standalone, integrated, and automated desktop system that processes five to seven DNA samples in 90 minutes in a closed, hands-off system. Rapid DNA is built to be operated by DHS field officers and agents. It is about the size of a laser printer, and can be operated in an office setting by anyone who can change a printer cartridge. It is also ruggedized to military requirements, and can be operated in hazardous field environments on generator power. Setup takes just 15 minutes. With success showing that Rapid DNA accurately verifies family relationships, additional DHS needs were identified to fight human trafficking along U.S. borders and reunify families following critical or mass-casualty incidents. This presentation will discuss the DHS needs for family relationship verification, AABB Standards, and Rapid DNA performance and field test results.
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