艾司西酞普兰引起的高泌乳素性溢乳

Deepthi Yedla, V. Sharmila
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引用次数: 0

摘要

乳溢是一年没有母乳喂养的妇女乳房分泌的乳白色分泌物。艾司西酞普兰是一种选择性血清素再摄取抑制剂(SSRI),由于其效力和耐受性,被认为是治疗抑郁症和焦虑症的一线药物。ssri类药物很少引起由催乳素水平升高引起的症状。增加血清素的抗抑郁药可能通过改善多巴胺神经传递而增加催乳素。在目前的研究中,我们提出了一例与艾司西酞普兰相关的高泌乳素血症性乳溢。一位32岁女性在使用艾司西酞普兰治疗焦虑后出现双侧乳房沉重和乳状分泌物,血清催乳素水平升高。停用艾司西酞普兰后,乳溢消失,泌乳素水平恢复正常。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Escitalopram-induced hyperprolactinemic galactorrhea
Galactorrhea is milky secretions from the breast in women who have not breast-fed for a year. Escitalopram, a selective serotonin reuptake inhibitor (SSRI), owing to its potency and tolerance, is regarded as the primary line drug in the management of depression and anxiety disorders. SSRIs may rarely cause symptoms brought on by enhanced prolactin levels. Antidepressants that increase serotonin may additionally cause a rise in prolactin by improving dopamine neurotransmission. In the current research, we present a case of hyperprolactinemic galactorrhea linked to escitalopram. A 32-year-old woman presented with bilateral breast heaviness and milky secretions after using escitalopram for anxiety and her serum prolactin level was found to be elevated. Galactorrhea disappeared and her prolactin level returned to normal after escitalopram was stopped.
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