Gibran Yusuf - 2015年欧洲青年研究者奖联合获得者

G. Yusuf, E. Konstantatou, M. Sellars, Dean Y. Huang, P. Sidhu, G. Yusuf
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摘要

方法▼血肿/肿瘤从数据库中识别,并由经验丰富的观察员回顾性审查。所有患者均接受睾丸超声检查(US),由经验丰富的观察人员使用高频换能器,采用MPUS标准技术,结合灰度、彩色多普勒、对比增强超声(CEUS)和应变弹性成像(SE)。记录的特征有;大小、位置、回声性、彩色多普勒信号、对比增强、弹性评分和应变比。随访记录。结果8例患者(平均年龄31岁,年龄25 ~ 43岁)共17例血肿(右睾丸11例,左睾丸6例,最大直径5 ~ 28mm)。钝性创伤(n=7)和手术(n=1)是之前的事件。灰度超音波显示清晰,椭圆形或圆形,主要是低回声和不均匀,周围(n=13)或中心位置(n=4)。3例超声造影显示彩色多普勒未见的分隔增强,4例外周边缘增强。16个病变行SE;平均应变比1.49(范围0.41-2.77),弹性评分≤3 (n=12)和5 (n= 4),随访超声检查均为良性。回顾性分析组织学证实的大小相似的肿瘤(精原细胞瘤、间质细胞瘤和非精原细胞瘤生殖细胞瘤分别为8例、5例和4例)。两组的人口统计学相似(平均年龄37岁,范围25-64岁)。灰度成像主要显示包膜下周围病变,主要是低回声或不均匀(n=16)。背景睾丸异常(n=6),最常见的发现是微石症。在超声造影上,所有病变均明确显示强化,并且在SE上主观坚硬(平均应变比6.04,范围0.61-15)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Gibran Yusuf – Joint Winner of Young Investigator Award Euroson 2015
Methods ▼ Hematomas/tumours were identified from a database and retrospectively reviewed by experienced observers. All patients underwent testicular ultrasonography (US), by experienced observers, using high frequency transducers, employing standard techniques of MPUS combining grey-scale, colour Doppler, contrast enhanced ultrasound (CEUS) and strain elastography (SE). Features recorded were; size, location, echogenicity, colour Doppler signal, contrast-enhancement, elasticity score and strain ratio. Follow-up was recorded. Results ▼ 17 haematomas (right testis n=11, left testis n=6, maximum diameter range 5–28mm) in 8 patients (mean age 31 years, range 25-43 years) were analysed. Blunt trauma (n=7) and surgery (n=1) were preceding events. Greyscale sonography demonstrated well-defined, oval or round, predominantly hypoechoic and heterogeneous, peripherally (n=13) or centrally located (n=4). Three demonstrated CEUS enhancement of septations not seen on colour Doppler and 4 peripheral rim enhancement. Sixteen lesions had SE performed; mean strain ratio was 1.49 (range 0.41–2.77), elasticity score ≤3 (n=12) and 5 (n= 4). All lesions were confirmed benign on follow-up sonography. Retrospective analysis with similar size histologically proven tumours was performed (seminoma, Leydig cell tumours and non seminomatous germ cell tumours n=8, n=5, n=4 respectively). Demographics were similar in both groups (mean age 37 years, range 25-64). Grayscale imaging demonstrated predominantly subcapsular peripheral lesions which were predominantly hypoechoic or heterogeneous (n=16). The background testis was abnormal in (n=6) with microlithiasis the most common findings. On CEUS all lesions definitively showed enhancement and were found to be subjectively hard on SE (mean strain ratio 6.04, range 0.61-15).
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