孕妇疟疾与血红蛋白相互作用的研究

Konne Oroma Ethel, Moore-Igwe Beatrice Wobiarueri, Chukwu Priya Homa, Chukuigwe-Igbere Orokwu Eziaku, Konne Joel Burabari, Konne Felix Eedee
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摘要

对在Bori综合医院(GHB)和Harcourt港Braithwaite纪念专科医院(BMSH)产前诊所就诊的孕妇的疟疾患病率进行了比较观察研究。400名女性参与了这项研究每个研究地点有200名女性。排除原因不明发热孕妇、艾滋病毒孕妇和服用抗疟疾药物孕妇。获得了参与者的同意并保密。获得了卫生部和选定的卫生设施的伦理批准。样本采集按照推荐的静脉切开术参考指南进行。采集的样品用氰氨基血红蛋白法检测血红蛋白,用吉姆萨染色法检测疟原虫。对百分比、频率进行统计分析,对描述性统计和推断p值=0.05进行统计分析。所有统计分析均使用社会科学统计软件包进行。发放了调查问卷,以获取他们的人口统计数据。孕妇血红蛋白水平8.0-10.9g /dl BMSH(17.9%)和GHB(35.9%)的疟疾患病率较高。感染与地区无关,p值< 0.05。应支持对妊娠期疟疾的认识。应治疗妊娠贫血,并紧急处理疟疾和妊娠贫血的合并症。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Study on Malaria and Haemoglobin Interaction in Pregnant Women
Comparative observational study was carried out on the prevalence of malaria among pregnant women attending antenatal clinics in General Hospital, Bori (GHB) and Braithwaite Memorial Specialist Hospital, Port Harcourt (BMSH).  Four hundred women were involved in this study of which two hundred per study location. Pregnant women with pyrexia of unknown origin, HIV and those on anti malarial drugs were excluded. Consents were obtained from participants and confidentiality upheld.  Ethical approval was obtained from the ministry of health and from the selected health facilities. Sample collection was performed according to the recommended reference guideline for phlebotomy. Collected samples were used to assay for Haemoglobin using cyanomethamoglobin method, and malaria parasite using the Giemsa staining technique.  Statistical analysis was performed for percentage, frequency, for descriptive statistics and inferences deduced at p-value=0.05. All statistical analyses were performed using Statistical Package for Social Sciences. Questionnaires were issued to obtain their demographic data.  The prevalence of malaria was high among pregnant women with haemoglobin level 8.0–10.9g/dl from BMSH (17.9%) and GHB (35.9%).  Infection was not dependent on locality at P-value < 0.05. Awareness of  malaria in pregnancy should be supported. Anaemia in pregnancy should be treated and comorbidity of malaria and anaemia in pregnancy should be handled with urgency.
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