Wiktor M. Kulesza, M. Wielgo, P. Węgrzyn, S. Tomczewski, O. Çetinkaya, Katarzyna Kordecka, Anna Galińska, Bartłomiej Bałamut, E. Auksorius, A. Foik, R. Zawadzki, M. Wojtkowski, D. Borycki, A. Curatolo
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Ultrafast volumetric imaging with a spatio-temporal optical coherence tomography (STOC-T) system for monitoring hemodynamics in mouse retinal vessels directly from structural data
We present a novel ultrafast imaging system using Spatio-Temporal Optical Coherence Tomography (STOC-T), capable of acquiring structural images of a mouse retina at a volumetric rate of 112 Hz. A calibrated fundus camera and white-light illumination aid the alignment of the mouse and the adjustment of the focal plane in the mouse retina for the STOC-T image. We extract pulsatile blood flow frequency and other hemodynamic parameters from multiple retinal and choroidal vessels from structural-only OCT images, highlighting the prospects of STOC-T for monitoring retinal hemodynamics in a simple way.
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