跨学科研究——心脏病学的未来

B. Rao
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通讯作者:B Hygriv Rao, kim医院,海德拉巴,泰伦加纳500003,印度。电子邮件:hygriv@hotmail.com本世纪惊人的技术创新推动了心血管医学在各个方面的指数级增长,超越了传统的界限。心脏病患者的最佳诊断和管理目前严重依赖于与该领域的子专业的互动以及其他医学和工程学科的贡献。心力衰竭(HF)人群的巨大负担暴露了在诊断、风险分层和医疗资源利用的经济审慎方面的挑战。放射学在心脏MRI和正电子发射断层扫描(PET)领域的进步已经成功地应对了这些挑战。心肌MRI (CMRI)的晚期钆增强(LGE)已被证明是心肌疤痕的可靠替代品,心肌疤痕是猝死和hf恶化的重要基础。1,CMRI的详细成像输入有助于精确定义心内膜和心外膜疤痕,准确评估心室功能,并精细描绘基底中的心律失常通道。此外,它在肥厚性心肌病和非缺血性心肌病(NICM)患者的预后方面也有很大的帮助。同样,PET在诊断新发心衰、室性心律失常和传导阻滞患者的结节病方面也有很大贡献。成像技术的进一步成熟无疑将完善诊断标准,简化决策算法。成像也使临床医生能够理解并有效地将解剖学与介入手术策略概念化联系起来。在主动脉夹层和动脉瘤以及经导管主动脉瓣介入治疗中尤其如此。手术的安全性和效果的提高与成像技术和操作员经验的提高同样重要。室性心动过速(VT)是一种致命的心律失常,通常用药物、消融术和植入式除颤器治疗。难治性室速和电风暴是一个具有高死亡率的具有挑战性的临床问题,而放射治疗已成为拯救这一困难临床中最意想不到的竞争者之一
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Interdisciplinary Research—Future of Cardiology
Corresponding author: B Hygriv Rao, KIMS Hospitals, Hyderabad, Telangana 500003, India. E-mail: hygriv@hotmail.com The spectacular innovations in technology in this century have fuelled the exponential growth of cardiovascular medicine in all dimensions eclipsing its conventional boundaries. Optimal diagnosis and management of cardiac patients is currently critically dependent on the interaction with sub-specialties in this field and contribution from other disciplines of medicine and engineering. The large burden of heart failure (HF) population has exposed the challenges in diagnosis, stratification of risk and economic prudence in utilization of healthcare resources. Advances in Radiology in the areas of cardiac MRI and positron emission tomography (PET) have succeeded in meeting some of these challenges. Late gadolinium enhancement (LGE) in cardiac MRI (CMRI ) has proven to be a reliable surrogate of myocardial scar which is the essential substrate for sudden death and worsening HF.1,2 Detailed imaging inputs from CMRI have helped to precisely define the endocardial and epicardial scar, assess accurately the ventricular function, and finely delineate the arrythmogenic channels in the substrate. Further it has aided substantially in prognostication in patients with substrates like hypertrophic cardiomyopathy and nonischemic cardiomyopathy (NICM). Similarly PET has contributed immensely in diagnosing sarcoidosis in patients presenting with new onset of HF, ventricular arrhythmias and conduction blocks. Further sophistication in imaging technology will undoubtedly refine the diagnostic criteria, and ease decision-making algorithms. Imaging has also enabled the clinician to understand and effectively correlate the anatomy in conceptualizing strategies for interventional procedures. This is particularly true in dissections and aneurysms of aorta, and trans-catheter interventions for aortic valves. The increasing safety and better outcomes of the procedures relate as much to the imaging technology as to the increasing operator experience. Ventricular tachycardia (VT) is a fatal arrhythmia conventionally treated with drugs, ablation and implantable defibrillators. Refractory VT and electrical storm is a challenging clinical problem with a high mortality, and radiotherapy has emerged as one of the least expected contender in the rescue of this difficult clinical
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