Ganesh Kalyanasundaram, Poh Yong Tan, Nilesh H Pawar, A. Taha
{"title":"肉芽肿合并多血管炎(韦格纳氏),伪装成不能解决的肺炎","authors":"Ganesh Kalyanasundaram, Poh Yong Tan, Nilesh H Pawar, A. Taha","doi":"10.29011/2638-003x.100017","DOIUrl":null,"url":null,"abstract":"Non-resolving pneumonia (NRP) includes those cases of presumed pneumonia that progress, resolve slowly, or fail to achieve complete resolution despite appropriate treatment [1]. Granulomatosis with Polyangiitis (GPA), previously known as Wegener’s granulomatosis is a multi-system disorder characterized by systemic necrotizing vasculitis which most commonly affects the small and medium vessels of the upper and lower respiratory tract and the kidneys [2,3]. Diagnosis of GPA requires a high index of suspicion, as the initial presentation is usually nonspecific, and most patients are usually diagnosed around 3-12 months from the onset of symptoms [4]. We present a case of a patient with nonresolving pneumonia who was eventually diagnosed with GPA.","PeriodicalId":431682,"journal":{"name":"Current trends in Internal Medicine","volume":"1 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2019-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Granulomatosis with Polyangiitis (Wegener’s) Masquerading as Non-Resolving Pneumonia\",\"authors\":\"Ganesh Kalyanasundaram, Poh Yong Tan, Nilesh H Pawar, A. Taha\",\"doi\":\"10.29011/2638-003x.100017\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Non-resolving pneumonia (NRP) includes those cases of presumed pneumonia that progress, resolve slowly, or fail to achieve complete resolution despite appropriate treatment [1]. Granulomatosis with Polyangiitis (GPA), previously known as Wegener’s granulomatosis is a multi-system disorder characterized by systemic necrotizing vasculitis which most commonly affects the small and medium vessels of the upper and lower respiratory tract and the kidneys [2,3]. Diagnosis of GPA requires a high index of suspicion, as the initial presentation is usually nonspecific, and most patients are usually diagnosed around 3-12 months from the onset of symptoms [4]. We present a case of a patient with nonresolving pneumonia who was eventually diagnosed with GPA.\",\"PeriodicalId\":431682,\"journal\":{\"name\":\"Current trends in Internal Medicine\",\"volume\":\"1 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-01-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Current trends in Internal Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.29011/2638-003x.100017\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current trends in Internal Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.29011/2638-003x.100017","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
非消退性肺炎(Non-resolving pneumonia, NRP)包括进展缓慢、消退缓慢或经过适当治疗后仍无法完全消退的疑似肺炎病例[1]。多血管炎肉芽肿病(Granulomatosis with Polyangiitis, GPA),以前被称为Wegener肉芽肿病,是一种多系统疾病,以全身性坏死性血管炎为特征,最常见于上、下呼吸道和肾脏的中小血管[2,3]。GPA的诊断需要高度的怀疑指数,因为最初的表现通常是非特异性的,大多数患者通常在症状出现后3-12个月左右被诊断出来[4]。我们提出了一个病例的患者不解决肺炎谁最终被诊断为GPA。
Granulomatosis with Polyangiitis (Wegener’s) Masquerading as Non-Resolving Pneumonia
Non-resolving pneumonia (NRP) includes those cases of presumed pneumonia that progress, resolve slowly, or fail to achieve complete resolution despite appropriate treatment [1]. Granulomatosis with Polyangiitis (GPA), previously known as Wegener’s granulomatosis is a multi-system disorder characterized by systemic necrotizing vasculitis which most commonly affects the small and medium vessels of the upper and lower respiratory tract and the kidneys [2,3]. Diagnosis of GPA requires a high index of suspicion, as the initial presentation is usually nonspecific, and most patients are usually diagnosed around 3-12 months from the onset of symptoms [4]. We present a case of a patient with nonresolving pneumonia who was eventually diagnosed with GPA.