妊娠期高血压综合征的预测与预防

Z Q Qian, C F Liu, Y X Chen
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摘要

根据中医辨证论治分析平均动脉压(MAP-2)可预测妊娠中期(小于24周)患者首次就诊时妊娠高血压综合征(HSP)的发生。将424例MAP-2≥12kPa的孕妇分为4组,给予预防性治疗:(1)对照组122例,不给予药物治疗;(2) Theragan组,102名女性;(3)中医(A)组100例,阴型肝肾虚证或无明显症状者给予芪菊地黄丸,阳型脾肾虚证给予肾芪丸;(4)中药(B)组100名妇女给予丹参加(A)组药物治疗。预测结果:(1)MAP-2 < 12kPa组HSP发生率为10。5%;MAP-2≥12kPa组为49.2%。差异是显著的。(2)大于等于12kPa的MAP-2阴虚率显著高于小于12kPa的MAP-2阴虚率。阴虚组的热休克蛋白率高于非阴虚组。HSP率上升至70。7% MAP-2大于等于12kPa伴有阴虚。预防结果:(1)4组患者HSP发生率分别为49.2%、30.4%、15%和14%。(2)经预防治疗,母婴均无不良反应。未发生子痫。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Prediction and prevention of hypertension syndrome of pregnancy].

Analysis of mean artery pressure (MAP-2) according to the differentiation of symptom complex of TCM can predict the occurrence of hypertension syndrome of pregnancy (HSP) at patients' first visit to hospital during their middle gestational period (less than 24 pregnant weeks). 424 pregnant women (MAP-2 greater than or equal to 12kPa) were divided into 4 groups and given preventive treatment as follows: (1) The control group, 122 women, no drugs were given; (2) the Theragan group, 102 women; (3) the TCM (A) group, 100 women, those with Liver-Kidney deficiency of Yin or no apparent signs were given Qiju Dihuang Wan, and those with Spleen-Kidney deficiency of Yang were given Shenqiwan; (4) the TCM(B) group, 100 women, were given Salvia miltiorrhiza plus (A) group's drugs. The results of prediction: (1) The occurrence rate of HSP in the MAP-2 less than 12kPa group was 10. 5%; in the MAP-2 greater than or equal to 12kPa group, 49.2%. The difference was significant. (2) The rate of deficiency of Yin in the MAP-2 greater than or equal to 12kPa was significantly higher than in the MAP-2 less than 12kPa. The rate of HSP in the deficiency of Yin was higher than in the nondeficiency of Yin. The rate of HSP increased to 70. 7% in the MAP-2 greater than or equal to 12kPa with deficiency of Yin. The results of prevention: (1) The occurrence rates of HSP in 4 groups were 49.2%, 30.4%, 15% and 14% respectively. (2) There was no side effect for mother and infant after preventive treatment. No eclampsia occurred.

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