J. Farrell, Zheng Lyu, Zhenyi Liu, H. Blasinski, Zhihao Xu, J. Rong, Feng Xiao, B. Wandell
{"title":"口腔癌筛查软原型成像系统","authors":"J. Farrell, Zheng Lyu, Zhenyi Liu, H. Blasinski, Zhihao Xu, J. Rong, Feng Xiao, B. Wandell","doi":"10.2352/issn.2470-1173.2020.7.iss-212","DOIUrl":null,"url":null,"abstract":"We are using image systems simulation technology to design a digital camera for measuring fluorescent signals; a first application is oral cancer screening. We validate the simulations by creating a camera model that accurately predicts measured RGB values for any spectral radiance.\n Then we use the excitationemission spectra for different biological fluorophores to predict measurements of fluorescence of oral mucosal tissue under several different illuminations. The simulations and measurements are useful for (a) designing cameras that measure tissue fluorescence and\n (b) clarifying which fluorophores may be diagnostic in identifying precancerous tissue.","PeriodicalId":121190,"journal":{"name":"Imaging Sensors and Systems","volume":"1 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2020-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"4","resultStr":"{\"title\":\"Soft-prototyping imaging systems for oral cancer screening\",\"authors\":\"J. Farrell, Zheng Lyu, Zhenyi Liu, H. Blasinski, Zhihao Xu, J. Rong, Feng Xiao, B. Wandell\",\"doi\":\"10.2352/issn.2470-1173.2020.7.iss-212\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"We are using image systems simulation technology to design a digital camera for measuring fluorescent signals; a first application is oral cancer screening. We validate the simulations by creating a camera model that accurately predicts measured RGB values for any spectral radiance.\\n Then we use the excitationemission spectra for different biological fluorophores to predict measurements of fluorescence of oral mucosal tissue under several different illuminations. The simulations and measurements are useful for (a) designing cameras that measure tissue fluorescence and\\n (b) clarifying which fluorophores may be diagnostic in identifying precancerous tissue.\",\"PeriodicalId\":121190,\"journal\":{\"name\":\"Imaging Sensors and Systems\",\"volume\":\"1 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-01-26\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"4\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Imaging Sensors and Systems\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.2352/issn.2470-1173.2020.7.iss-212\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Imaging Sensors and Systems","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2352/issn.2470-1173.2020.7.iss-212","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Soft-prototyping imaging systems for oral cancer screening
We are using image systems simulation technology to design a digital camera for measuring fluorescent signals; a first application is oral cancer screening. We validate the simulations by creating a camera model that accurately predicts measured RGB values for any spectral radiance.
Then we use the excitationemission spectra for different biological fluorophores to predict measurements of fluorescence of oral mucosal tissue under several different illuminations. The simulations and measurements are useful for (a) designing cameras that measure tissue fluorescence and
(b) clarifying which fluorophores may be diagnostic in identifying precancerous tissue.
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