口腔黏膜下纤维化分期与不同生活习惯的临床病理评价及相关性研究

Shweta Singh, Pravin Gaikwad, G. Sapra, Raju Chauhan
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引用次数: 2

摘要

目的:口腔黏膜下纤维化(OSF)是一种癌前病变,主要与咀嚼槟榔有关。本研究旨在将与OSF相关的病因(持续时间、频率、类型和咀嚼习惯)与临床分级和组织学分期相关联。方法:共纳入50例临床和组织病理学诊断的OSF病例。对每位患者进行详细的临床检查;强调他们的习惯。对每个病例进行临床分级和组织学分期,并按规定格式记录资料。统计学分析采用卡方检验。结果与观察:共纳入50例受试者,男女比例为7.3:1,年龄20 ~ 30岁。46%的受试者有单独咀嚼古特哈的习惯,33.3%的受试者有古特哈和烟草相关的习惯,平均±S.D =32±11.51。结论:咀嚼口服液是口腔黏膜下纤维化发生的重要因素,咀嚼口服液是口腔黏膜下纤维化发生的重要因素。食用槟榔果制品的时间、频率和种类对OSF的发生和严重程度有影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Clinico-Pathological Evaluation and Correlation of Stages of Oral Submucous Fibrosis with Different Habits
Objective: Oral Submucous Fibrosis (OSF) is a precancerous condition and is mainly associated with the chewing of areca nut. This study was undertaken to correlate the etiological factors (duration, frequency, style and chewing habit) associated with OSF with clinical grading and histological staging. Methodology: A total of 50 clinically and histopathologically diagnosed cases of OSF were included in the study. Detailed clinical examination of each patient was done; emphasizing on their habit. Clinical grading and histological staging of each case was done and the data was recorded in a prescribed format. Statistical analysis was done using chi-square test. Result and observation: A total of 50 subjects were studied, with a male to female ratio of 7.3:1 with age range of 20-30 year. Gutkha-chewing habit alone was identified in 46% of subjects and those associated with gutkha and tobacco were 33.3% with a mean ± S.D =32 ± 11.51. Conclusion: The widespread habit of chewing gutkha plays a major role in the development of Oral Submucous Fibrosis than any other habit. The duration and frequency of its use and type of areca nut product has effect on the incidence and severity of OSF.
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