用于彗星分析的半自动评分工具

2015 IEEE 15th International Conference on Bioinformatics and Bioengineering (BIBE) Pub Date : 2015-11-02 DOI:10.1109/BIBE.2015.7367718

E. Kiziltan, E. Yurtçu

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引用次数: 7

摘要

彗星试验或单细胞凝胶电泳是一种广泛使用的DNA损伤评估方法。该方法的结果可以在显微镜下进行评分，无论是用肉眼还是自动系统。在这项研究中，我们提出了在我们实验室开发的半自动彗星测定分析工具。用该工具得到的结果与全自动共享软件的结果进行了比较。初步结果表明，该软件是一种准确、可靠的彗星分析评价工具。

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Semi-automatic scoring tool for comet assay

Comet assay or single-cell gel electrophoresis is a widely used method for DNA damage assessment. The results of the method can be scored under microscopic examination either with the naked eye or automated systems. In this study, we present a semi-automatic comet assay analysis tool that was developed in our laboratory. The results obtained with our tool were compared with that of fully automatic shareware software. The preliminary results suggest that the presented semi-automatic software is an accurate and reliable tool for evaluation of comet assay.

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2015 IEEE 15th International Conference on Bioinformatics and Bioengineering (BIBE)

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