慢性肾衰竭的进展。

Child nephrology and urology Pub Date : 1991-01-01
C Polito, A La Manna, A N Olivieri, M L Cartiglia, G Bonomo, A Di Toro, N Todisco, R Del Gado
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引用次数: 0

摘要

对40例慢性肾衰竭(CRF)患儿保守治疗至少1年(范围1-12年)的肌酐清除率(CCr)恶化率进行了研究。肾小球病变(G)的CCr恶化率显著(p < 0.01)高于发育不良(H)和血管性肾病(VN),遗传性肾病(HN)的CCr恶化率显著(p < 0.01)高于VN。H和HN之间以及H和VN之间CCr恶化率的差异不能以诊断年龄不同或高血压患病率不同来解释。这些数据表明,原发性肾脏疾病是决定慢性肾功能衰竭进展的重要因素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Progression of chronic renal failure.

The deterioration rate of creatinine clearance (CCr) was studied in 40 children with chronic renal failure (CRF) on conservative treatment followed up for at least 1 year (range 1-12). The deterioration rate of CCr was significantly (p less than 0.01) higher in glomerulopathies (G) than in hypoplasias (H) and in vascular nephropathies (VN) and significantly (p less than 0.01) higher in hereditary nephropathies (HN) than in VN. The differences in the deterioration rate of CCr between H and HN and between H and VN were not explainable on the basis of the different age at diagnosis or of the different prevalence of hypertension. These data indicate that the primary renal disease is important in determining the progression of CRF.

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