基因调控网络的重构:问题与方法

2009 2nd IEEE International Conference on Computer Science and Information Technology Pub Date : 2009-09-11 DOI:10.1109/ICCSIT.2009.5234743

Zhongming Han, Dagao Duan, Wenzheng Li, Hongzhi Liu

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引用次数: 1

摘要

了解基因表达的调控机制是系统生物学的核心。利用真实基因表达微阵列数据重构基因调控网络已引起广泛关注。本文详细讨论了遗传调控网络重构的两个基本问题:网络拓扑结构和重构方法。提出了一些可能的改进算法。

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Reconstructing genetic regulation network: Problems and methods

Understanding regulation mechanism of gene expression is the kernel of system biology. Reconstructing genetic regulation network from real gene expression microarray data has draw a lot of attention. Two basic problems for reconstructing genetic regulation network: the network topology and reconstructing method are detailed discussed in this paper. Some possible improved algorithms are proposed.

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2009 2nd IEEE International Conference on Computer Science and Information Technology

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