O. Aldemir, Mehmet Rıfat Göklü, M. Özer, Alper Ileri, Pınar Tuğçe Özer, Ö. Özdemir, Can Ata, S. Kurt
{"title":"口服补铁对妊娠期糖尿病危险人群中非贫血孕妇糖代谢的影响","authors":"O. Aldemir, Mehmet Rıfat Göklü, M. Özer, Alper Ileri, Pınar Tuğçe Özer, Ö. Özdemir, Can Ata, S. Kurt","doi":"10.46328/aejog.v4i3.131","DOIUrl":null,"url":null,"abstract":"Aim: There are opinions about the negative effects of the increase in iron storages or plasma iron levels during pregnancy on glucose metabolism. We aimed to investigate the effects of oral iron supplementation on glucose metabolism in non-anemic pregnant women who are in the risk group for gestational diabetes mellitus. \nMaterial and methods: While oral iron supplementation of 40 mg/day was givento 41 pregnant women in the study group (Group I) for eight weeks, oral iron supplementation was not givento 35 pregnant women in the control group (Group II). 100 g oral glucose tolerance test (OGTT) was applied for the diagnosis of GDM in pregnant women whose 50 g OGTT results were positive. Analyzing the results between groups. \nResults:There was no significant difference between the two groups in terms of mean fasting plasma glucose (FPG) value (p: 0.185), GDM (p:0.292) and mean results of 50gr OGLT (p: 0.109).A total of 26 pregnant women with 50 gr OGLT positive were applied 100 gr OGTT for diagnostic purposes. \nConclusion:It was concluded that 40 mg/day oral iron supplement used from the first trimester in pregnant women in the risk group for GDM did not have a significant negative effect on glucose metabolism and did not cause an increase in the risk of GDM.","PeriodicalId":159256,"journal":{"name":"Aegean Journal of Obstetrics and Gynecology","volume":"63 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2022-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"effect of oral iron supplementation on glucose metabolism in non-anemic pregnant women who are in the risk group for gestational diabetes mellitus\",\"authors\":\"O. Aldemir, Mehmet Rıfat Göklü, M. Özer, Alper Ileri, Pınar Tuğçe Özer, Ö. Özdemir, Can Ata, S. Kurt\",\"doi\":\"10.46328/aejog.v4i3.131\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Aim: There are opinions about the negative effects of the increase in iron storages or plasma iron levels during pregnancy on glucose metabolism. We aimed to investigate the effects of oral iron supplementation on glucose metabolism in non-anemic pregnant women who are in the risk group for gestational diabetes mellitus. \\nMaterial and methods: While oral iron supplementation of 40 mg/day was givento 41 pregnant women in the study group (Group I) for eight weeks, oral iron supplementation was not givento 35 pregnant women in the control group (Group II). 100 g oral glucose tolerance test (OGTT) was applied for the diagnosis of GDM in pregnant women whose 50 g OGTT results were positive. Analyzing the results between groups. \\nResults:There was no significant difference between the two groups in terms of mean fasting plasma glucose (FPG) value (p: 0.185), GDM (p:0.292) and mean results of 50gr OGLT (p: 0.109).A total of 26 pregnant women with 50 gr OGLT positive were applied 100 gr OGTT for diagnostic purposes. \\nConclusion:It was concluded that 40 mg/day oral iron supplement used from the first trimester in pregnant women in the risk group for GDM did not have a significant negative effect on glucose metabolism and did not cause an increase in the risk of GDM.\",\"PeriodicalId\":159256,\"journal\":{\"name\":\"Aegean Journal of Obstetrics and Gynecology\",\"volume\":\"63 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-12-29\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Aegean Journal of Obstetrics and Gynecology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.46328/aejog.v4i3.131\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Aegean Journal of Obstetrics and Gynecology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.46328/aejog.v4i3.131","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
目的:关于妊娠期铁储存或血浆铁水平的增加对糖代谢的负面影响,目前有一些观点。我们的目的是研究口服补铁对妊娠期糖尿病高危人群中非贫血孕妇糖代谢的影响。材料与方法:研究组41例孕妇(第一组)口服补铁40 mg/天,持续8周,对照组35例孕妇(第二组)不口服补铁,对50 g OGTT阳性的孕妇应用100 g口服糖耐量试验(OGTT)诊断GDM。组间结果分析。结果:两组患者空腹血糖(FPG)平均值(p: 0.185)、GDM (p:0.292)和50克OGLT平均结果(p: 0.109)无显著差异。共有26例50克OGLT阳性的孕妇应用100克OGTT进行诊断。结论:GDM危险组孕妇从妊娠早期开始口服补铁40 mg/d对糖代谢无显著负面影响,未引起GDM风险增加。
effect of oral iron supplementation on glucose metabolism in non-anemic pregnant women who are in the risk group for gestational diabetes mellitus
Aim: There are opinions about the negative effects of the increase in iron storages or plasma iron levels during pregnancy on glucose metabolism. We aimed to investigate the effects of oral iron supplementation on glucose metabolism in non-anemic pregnant women who are in the risk group for gestational diabetes mellitus.
Material and methods: While oral iron supplementation of 40 mg/day was givento 41 pregnant women in the study group (Group I) for eight weeks, oral iron supplementation was not givento 35 pregnant women in the control group (Group II). 100 g oral glucose tolerance test (OGTT) was applied for the diagnosis of GDM in pregnant women whose 50 g OGTT results were positive. Analyzing the results between groups.
Results:There was no significant difference between the two groups in terms of mean fasting plasma glucose (FPG) value (p: 0.185), GDM (p:0.292) and mean results of 50gr OGLT (p: 0.109).A total of 26 pregnant women with 50 gr OGLT positive were applied 100 gr OGTT for diagnostic purposes.
Conclusion:It was concluded that 40 mg/day oral iron supplement used from the first trimester in pregnant women in the risk group for GDM did not have a significant negative effect on glucose metabolism and did not cause an increase in the risk of GDM.