COVID-19 seroprevalence study of an Indian Diagnostic Laboratory - Report on gender and age analysis

In COVID-19 the extent of the impact on exposure, symptoms, recovery remains minimally explored as the spectrum is challenging to study across geographies. The aim of our study report was to explore seroprevalence in a pan-India cohort of Asian Indians across different age groups. Covid-19 antibodies were tested from a total of 1,36,210 Asian Indians inclusive of 97,124 males and 39,086 females, respectively. Testing for covid-19 antibodies was done by electrochemiluminescence immunoassay (ECLIA) and enzyme-linked immunosorbent assay (ELISA). Analysis for seroprevalence found the frequency to be 19%. The percent positives were higher among females at 21%, compared to males at 19%, and the difference was found to be statistically significant at p < 0.0001. Further, age group-wise analysis found seroprevalence between age groups of 21 - 80 years to be significant at p < 0.0001. Our study found higher seroprevalence among females, which is in line with many small cohort studies published online.