体外环境下基于法拉第法的磁光法血糖测量用于医学诊断

I. Yariçi, B. Cetintas, A. J. Pahnvar, Y. Ozturk, M. Engin
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引用次数: 0

摘要

在本研究中,为了利用葡萄糖的光学活性和磁场下光的偏振变化来帮助糖尿病患者测量血糖,正在开发一种测定血模中葡萄糖浓度并在体外条件下运行的光学系统[4,5]。在设计的光学系统中,偏振角的机械改变会导致用户和系统的误差。另外,该研究旨在通过磁光偏振玻璃(其Verdet常数是已知的)在线圈内进行修改来防止这种误差的机械根源。在体外环境下,采用基于法拉第方法的磁光法测量了糖溶液的极化角偏差。结果表明,理论计算值与实验测量值基本一致。大多数血糖测量方法会给患者带来不适(疼痛),并有感染的风险[1]。基于光学的方法是可选择的方法之一[2,3]。结果表明,葡萄糖浓度溶液的光极化发生交替,表明葡萄糖具有旋光性。另一个改变光偏振的参数是通过光的传播施加的磁场。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Glucose measuring by faraday approach based magneto-optical method in-vitro environment for medical diagnosis
In this study, in order to help the blood glucose measurement on diabetic patients by using optical activity of glucose and the changing polarization of light under a magnetic field, an optical system determining the glucose concentration in the blood phantom and operating in-vitro conditions is being developed [4,5]. In that designed optical system, the alteration of the polarization angle mechanically will lead to the user and system errors. Alternatively, the study aims to prevent the mechanical origin of this error via the magneto-optical polarization glass, whose Verdet constant is known, modified inside an coil. In the study, the polarization angle deviations from the sugar solution was measured by the Faraday approach based magneto-optical method in an in-vitro environment. It was observed that the calculated theoretical values and measured experimental data are compatible. Most blood glucose measuring methods cause discomfort (pain) for the patient as well as have the risk of infection[1]. Tthe optic based approach is one of the alternatively considered methods [2,3]. It shows that the solution of glucose concentration alternates the light polarization, which means the glucose is optically active. Another parameter that changes the polarization of light is the applied magnetic field via the propagation of light.
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