多发性硬化症的神经保护策略:推进保护神经元功能和促进修复的治疗方法

María Alejandra Nieto‐Salazar
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引用次数: 0

摘要

多发性硬化症(MS)是一种以炎症和脱髓鞘为特征的中枢神经系统(CNS)慢性自身免疫性疾病,导致严重的残疾和社会经济负担。由于MS缺乏明确的治疗方法,因此迫切需要探索能够保持神经元功能并阻止疾病进展的神经保护策略。本文全面回顾了目前的知识和新兴的治疗方法,以保护神经功能和促进ms患者的修复。综述强调了神经保护策略,包括免疫调节疗法、神经修复药物和生活方式改变,这些策略在临床研究中显示出前景。此外,本文还讨论了基于个体MS特征的个性化治疗方法的潜力,以及新兴神经再生疗法的使用,以提高患者的生活质量和预防复发。通过加强我们对这些神经保护策略的理解,希望可以实现更有效的MS管理,减少疾病对患者生活的影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Neuroprotective Strategies for Multiple Sclerosis: Advancing Therapeutic Approaches to Preserve Neuronal Function and Promote Repair
Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system (CNS) characterized by inflammation and demyelination, leading to substantial disability and socioeconomic burden. With the absence of a definitive cure for MS, there is a critical need to explore neuroprotective strategies that can preserve neuronal function and impede disease progression. This article provides a comprehensive review of current knowledge and emerging therapeutic approaches to preserve neuronal function and promote repair in individuals with MS. The review highlights neuroprotective strategies, including immunomodulatory therapies, neuroreparative agents, and lifestyle modifications, that have shown promise in clinical studies. Additionally, the article discusses the potential of personalized treatment approaches based on individual MS profiles and the use of emerging neuroregenerative therapies to improve patients' quality of life and prevent relapses. By enhancing our understanding of these neuroprotective strategies, it is hoped that more effective management of MS can be achieved, reducing the disease's impact on patient's lives.
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