调强弧线治疗胸段食管癌在常规直线上的应用研究

Ruohui Zhang, W. Bai, Yulan Gao, Z. Chi
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引用次数: 1

摘要

体积调制电弧治疗(VMAT)作为一种新技术,不仅可以产生相似或更好的剂量分布,而且可以减少治疗时间和监测单位(MU)。然而,VMAT只能在新一代加速器上实施,如Varian Rap-idArc和Elekta Synergy,这使得大多数现有的直线加速器无法在VMAT中交付。本研究的目的是探讨在常规直线加速器上应用等剂量率IMAT,通过与IMRT技术的比较,评价IMAT对胸段食管癌患者的治疗效果,为临床治疗提供指导。结果表明,在繁忙的癌症中心,在常规varian 23EX直线机上对胸段食管癌实施IMAT计划可以顺利、快速地进行。与IMRT技术相比,IMAT方案可以满足临床需求,具有相当的OAR和提高的PTV CI,可以缩短治疗时间和高剂量照射量,同时增加健康组织的治疗MU和低剂量照射量以及肺V5和V10的体积。这一点在临床实施时需要注意。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Study of Implementation of Intensity Modulated Arc Therapy (IMAT) for Thoracic Esophageal Carcinoma on Conventional Linac
Volumetric-modulated arc therapy(VMAT), as novel technology not only can produce similar or better dose distributions, but also can reduce treatment time and the monitor units (MU). However, VMAT can only be implement-ed on the new generation accelerators such as the Varian Rap-idArc and Elekta Synergy, which prevents most existing linacs from delivering in VMAT. The purpose of this study is to investigate using constant dose rate IMAT on conventional linear accelrator, by comparing with the IMRT technology to evaluate the performance of IMAT on thoracic esophageal carcinoma patients and then provide guidance for clinical treatment. The results show that thoracic esophageal carci-noma can be implemented IMAT plans on conventional Vari-an 23EX Linac for smoothly and quickly at busy cancer center. Comparing with the IMRT techonology IMAT plans can meet the clinical demand, gives comparable OAR and improved CI of PTV, can reduce treatment time and high dose irradiated volume, while increase the treatment MU and low dose irra-diated volume of healthy tissues and the volume of the lung V5 and V10. This point needs to pay attention to implementation in clinical.
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