{"title":"PROFILE: Katalin Karikó","authors":"Jean E. Schelhorn, J. Herbers","doi":"10.1093/oso/9780197512715.003.0006","DOIUrl":null,"url":null,"abstract":"Katalin Karikó is a molecular biologist who became intrigued with the idea of using messenger RNA (mRNA) for therapeutic purposes more than 30 years ago. Messenger RNA is produced within cells by encoding information in DNA, and it directs the production of proteins. Her work paved the way for use of synthetic mRNA to prime the immune system of a host (like you and us) against viruses. mRNA vaccines are in widespread use for the first time as we battle the SARS-CoV-2 virus that causes COVID-19....","PeriodicalId":235446,"journal":{"name":"Beyond Discovery","volume":"26 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2022-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Beyond Discovery","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1093/oso/9780197512715.003.0006","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
Katalin Karikó是一位分子生物学家，他在30多年前就对使用信使RNA (mRNA)进行治疗的想法产生了兴趣。信使RNA是通过编码DNA中的信息在细胞内产生的，它指导蛋白质的产生。她的工作为使用合成mRNA来启动宿主(像你和我们)的免疫系统来对抗病毒铺平了道路。mRNA疫苗首次被广泛使用，因为我们正在与导致COVID-19的SARS-CoV-2病毒作斗争....
Katalin Karikó is a molecular biologist who became intrigued with the idea of using messenger RNA (mRNA) for therapeutic purposes more than 30 years ago. Messenger RNA is produced within cells by encoding information in DNA, and it directs the production of proteins. Her work paved the way for use of synthetic mRNA to prime the immune system of a host (like you and us) against viruses. mRNA vaccines are in widespread use for the first time as we battle the SARS-CoV-2 virus that causes COVID-19....
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