利用模糊分辨矩阵预测骨髓移植后患者的生存状况

Mahendra Kumar Gourisaria, Ayush Patel, Rajdeep Chatterjee, B. Sahoo
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摘要

骨髓移植(BMT),也被称为干细胞移植,是一种用健康细胞代替不健康细胞的骨髓的医学治疗方法。骨髓移植有助于治疗各种类型的癌症,如淋巴瘤、白血病和其他影响骨髓的疾病。能够预测患者是否能够承受骨髓移植对医生和患者都是非常有利的,因为这种预测可以挽救生命。在本文中,我们利用机器学习分类器,借助模糊可辨矩阵(FDM)和主成分分析(PCA)两种特征选择过程,预测了骨髓移植后患者的生存状态。我们计算了每个分类模型的准确率得分、精度得分、召回得分和ROC-AUC得分,并绘制了混淆矩阵,以便更好地分析结果。我们还强调了机器学习分类器使用两种方法给出的结果的比较,其中第一种方法在清洗数据集进行训练和测试后考虑每个特征,而在第二种方法中,我们通过实现主成分分析(PCA)和模糊可分辨矩阵(FDM)进行特征选择。利用模糊分辨矩阵处理选择的特征进行训练,得到了最优的训练结果。准确率为0.9523,精密度为1.0,召回率为0.9259,ROC-AUC为0.9444。与其他方法相比,ADA Boost与FDM具有最少的训练量(64689 $\mu$s)和测试时间(5021 $\mu$s)。也可以得出结论,与其他传统的特征选择技术相比,使用FDM方法进行特征选择将获得更好的结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Predicting the Survival Status of Patient after Bone Marrow Transplant Using Fuzzy Discernibility Matrix
Bone Marrow Transplant (BMT), also known as Stem Cell Transplant, is a type of medical treatment in which bone marrow having unhealthy cells is replaced by healthy cells. Bone Marrow Transplant helps to cure various types of cancer like lymphoma, leukemia, and other diseases that affect the bone marrow. Being able to predict if a patient can withstand a Bone Marrow Transplant can be very advantageous for doctors and patients as this prediction can be life-saving. In this paper, we have predicted the survival status of patients after Bone Marrow Transplant with the help of machine learning classifiers with the help of two feature selection processes known as the Fuzzy Discernibility Matrix (FDM) and Principal Component Analysis (PCA). We have calculated the Accuracy score, Precision Score, Recall Score, and ROC-AUC score for every classification model, and a confusion matrix is also plotted for a better analysis of the result. We have also highlighted the comparison of results given by machine learning classifiers using two approaches, where the first approach considers every feature after cleaning the dataset for training and testing, and in the second approach, we have performed feature selection by implementing Principal Component Analysis (PCA) and Fuzzy Discernibility Matrix (FDM). The best results were given by ADA Boost when trained using the features selected by the process of the Fuzzy Discernibility Matrix. It achieved an accuracy score of 0.9523, 1.0 precision score, 0.9259 recall score, and 0.9444 ROC-AUC scores. ADA Boost along with FDM had the least amount of training (64689 $\mu$s) and testing time (5021 $\mu$s) when compared with other approaches. It can also be concluded that using the FDM approach for feature selection will give better results as compared to other traditional feature selection techniques.
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