库尔德斯坦地区伊拉克人的COVID-19疫苗副作用:一项横断面研究

Nsc Nursing Pub Date : 2022-03-01 DOI:10.32549/opi-nsc-63
R. Abdullah, A. Tahir, Dlkhosh Ramadhan, Z. Mustafa, Kawther M. Galary
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摘要

背景:世界各地都对SARS-CoV-2疫苗的安全性和副作用表示担忧。新冠肺炎疫苗的不良反应对公众对疫苗的信任起到了关键作用。目前的研究旨在为BNT163b2 mRNA COVID-19疫苗(Pfizer-BioNTech®)的副作用提供证据;ChAdOx1 nCoV-19疫苗(AstraZeneca®);BBIBP-CorVvaccine(国药控股®)COVID-19疫苗。材料与方法:横断面研究设计于2021年4月26日至2021年6月3日进行。选取调查对象采用方便抽样;对强制性选择题问卷进行人脸效度测试,包括被调查者的人口学特征、冠状病毒相关记忆、冠状病毒疫苗的副作用持续时间,并采用描述性统计对数据进行分析。结果:588名参与者参加了本研究。ChAdOx1 nCoV-19疫苗的比例为49.7%,其次是BNT163b2 mRNA COVID-19疫苗和BBIBP-CorV(39.5%和10.9%)。最常见的主诉是头痛(61.2%),其次是疫苗注射部位不适(58.8%)、疲劳(49.7%)、发烧(48.3%)、肌肉不适(42.9%),大约(10.5%和10.2%)分别有注射部位肿胀和恶心。大多数受访者(25.2%)和(41%)在接种疫苗后出现1至2天的症状,只有一小部分(3.7%)的症状持续了一个月以上。ChAdOx1 nCoV-19疫苗处理了53%的副作用,其次是BNT163b2 mRNA COVID-19疫苗(42%)和BBIBP-CorV疫苗(5%)。结论:观察到各种局部和全身疫苗副作用的发生率,如头痛、发烧和注射部位疼痛。几乎所有受试者症状轻微,耐受性良好。阿斯利康疫苗副作用最大,辉瑞疫苗次之,国药疫苗最小。更多关于疫苗接种安全和公众意识的独立研究对于提高公众对疫苗的信任至关重要。关键词:COVID-19;疫苗;副作用;患病率;横断面设计。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
COVID-19 Vaccines Side Effects Among Iraqi people In Kurdistan Region: A cross-sectional study
Background: Communities around the world have expressed concern about the safety and side effects of SARS-CoV-2 vaccines. The adverse effects of the Covid-19 vaccines played a critical role in public trust in the vaccines. The current study aimed to provide evidence on the side effects of the BNT163b2 mRNA COVID-19 vaccine (Pfizer-BioNTech®); ChAdOx1 nCoV-19 vaccine (AstraZeneca®); BBIBP-CorVvaccine (Sinopharm®) COVID-19 vaccines.  Material and Methods: A cross-sectional study design was performed from April 26th, 2021, to June 3rd, 2021. Convenience sampling was used to select respondents; face validity was performed to the mandatory multiple-choice items questionnaire to cover the respondent’s demographic characteristics, coronavirus-19 related anamneses, and the side effect duration of coronavirus-19 vaccines, the data were analyzed by using descriptive statistics. Results: The 588 participants enrolled in the current study. ChAdOx1 nCoV-19 vaccine received 49.7%, followed by BNT163b2 mRNA COVID-19 vaccine and BBIBP-CorV (39.5% and 10.9%). The most common complaint was headache (61.2%), followed by vaccine injection site discomfort (58.8%), fatigue (49.7%), fever (48.3%), muscle discomfort (42.9%), and approximately (10.5% and 10.2%) had injection site swelling and nausea, respectively. Most of those surveyed had post-vaccine symptoms for one to two days (25.2%), (41%), and only a small percentage (3.7%) experienced them for over one month. ChAdOx1 nCoV-19 vaccine handled 53% of the side effects, followed by BNT163b2 mRNA COVID-19 vaccine (42%) and BBIBP-CorV vaccines (5%). Conclusion: Prevalence of various local and systemic vaccines side effects, such as headache, fever, and pain at the injection site, was observed. Almost all participants had mild symptoms and were well-tolerated .AstraZeneca® vaccine has the most side effects, followed by the Pfizer® vaccine, and the Sinopharm® vaccine has the least. More independent studies on vaccination safety and public awareness are critical to improving public trust in vaccines. Keywords: COVID-19; Vaccines; Side effects; Prevalence; Cross-sectional design.
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