{"title":"内源性阿片系统在抑郁症安慰剂反应中的可能作用。","authors":"F. Lichtigfeld, M. Gillman","doi":"10.1017/S1461145701002735","DOIUrl":null,"url":null,"abstract":"We read, with interest, the paper by Khan et al. (2001), which confirms earlier conclusions that approximately 75% of any treatment effect caused by antidepressants is held to be in common with that attributed to a placebo response alone (Kirsch and Sapirstein, 1998). Kirsch and Sapirstein (1998) concluded from their work that only 25% of the response to antidepressants was uniquely related to their specific therapeutic action.","PeriodicalId":394244,"journal":{"name":"The International Journal of Neuropsychopharmacology","volume":"32 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2002-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"4","resultStr":"{\"title\":\"Possible role of the endogenous opioid system in the placebo response in depression.\",\"authors\":\"F. Lichtigfeld, M. Gillman\",\"doi\":\"10.1017/S1461145701002735\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"We read, with interest, the paper by Khan et al. (2001), which confirms earlier conclusions that approximately 75% of any treatment effect caused by antidepressants is held to be in common with that attributed to a placebo response alone (Kirsch and Sapirstein, 1998). Kirsch and Sapirstein (1998) concluded from their work that only 25% of the response to antidepressants was uniquely related to their specific therapeutic action.\",\"PeriodicalId\":394244,\"journal\":{\"name\":\"The International Journal of Neuropsychopharmacology\",\"volume\":\"32 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2002-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"4\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The International Journal of Neuropsychopharmacology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1017/S1461145701002735\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The International Journal of Neuropsychopharmacology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1017/S1461145701002735","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 4
摘要
我们饶有兴趣地阅读了Khan et al.(2001)的论文，该论文证实了早期的结论，即抗抑郁药引起的任何治疗效果中约有75%被认为与单独归因于安慰剂反应的效果相同(Kirsch和Sapirstein, 1998)。Kirsch和Sapirstein(1998)从他们的工作中得出结论，对抗抑郁药的反应中只有25%是与它们的特定治疗作用唯一相关的。
Possible role of the endogenous opioid system in the placebo response in depression.
We read, with interest, the paper by Khan et al. (2001), which confirms earlier conclusions that approximately 75% of any treatment effect caused by antidepressants is held to be in common with that attributed to a placebo response alone (Kirsch and Sapirstein, 1998). Kirsch and Sapirstein (1998) concluded from their work that only 25% of the response to antidepressants was uniquely related to their specific therapeutic action.
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