2022年埃塞俄比亚南部阿瓦萨大学综合专科医院新生儿重症监护病房新生儿败血症程度及其预测因素

Temesgen Geta, Tsiyon Kassa, Eskinder Israel
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摘要

背景:新生儿败血症是全球新生儿死亡的主要原因,在低收入和中等收入国家以及包括埃塞俄比亚在内的发展中国家,分别占新生儿死亡率的15%和30%。尽管埃塞俄比亚政府为预防新生儿死亡率和发病率作出了各种努力,但与新生儿死亡率有关的败血症仍然很高。因此,本研究的目的是评估埃塞俄比亚南部阿瓦萨大学综合专科医院新生儿重症监护病房收治的新生儿脓毒症的严重程度及其影响因素。方法与材料:于2022年1 - 2月在埃塞俄比亚南部哈瓦萨大学综合专科医院进行了基于设施的横断面研究。本研究采用系统随机抽样的方法,选取216对入住重症监护病房的新生儿-母亲作为研究对象。采用结构化问卷收集数据。数据录入EPI data 3.1版本,传输至SPSS 25版本进行数据分析。对p值<0.05与因变量相关的预测变量进行多元回归分析。结果:新生儿败血症74例(34.3%)入院。在脓毒症(AOR=2.9, 95% CI(1.5 ~ 5.6))、最后一次妊娠(AOR=2.8, 95% CI(1.0 ~ 7.3))、更频繁的阴道检查(AOR=2.6, 95% CI(1.3 ~ 5.3))、教育水平不能读写(AOR=5.4, 95% CI(1.0 ~ 27.7))、低出生体重(AOR=5.4, 95% CI(3.0 ~ 9.8))和接受非熟练卫生工作者的护理(AOR=2.7)之前进行手术。95%的CI(1.5 ~ 4.9)与新生儿脓毒症在多变量中显著相关,p值小于0.05。结论:本研究表明新生儿脓毒症的患病率仍然很高。因此,应在导致新生儿死亡和进一步并发症之前立即采取行动。该研究仅使用医生诊断来确认新生儿败血症,这可能会影响其患病率,需要进一步调查。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Magnitude of sepsis and its predictors among neonates admitted to neonatal intensive care unit at Hawassa University comprehensive specialized hospital in Southern Ethiopia 2022
Background: Neonatal sepsis is a leading cause of neonatal death across the globe, which accounted for 15% and 30% of neonatal mortality in low and middle-income countries and developing countries including Ethiopia, respectively. Despite various efforts have been made by the Ethiopian government to prevent neonatal mortality and morbidity, sepsis-related to neonatal mortality is still high. So the objective of this study was to assess the magnitude and affecting factors of neonatal sepsis among neonates admitted to neonate intensive care units in Hawassa University Comprehensive Specialized Hospital, Southern Ethiopia. Methods and materials: Facility based cross-sectional study was conducted from January to February 2022 at Hawassa university comprehensive specialized hospital, Southern Ethiopia. A total of 216 neonate-mother pairs who were admitted to the intensive care unit was included in the study and a systematic random sampling technique was used to select study participant. A structured questionnaire was used to collect data. The data was entered into EPI Data 3.1 version and transported to SPSS version 25 for data analysis. Multi regression analysis was done for predictor variables associated at p-value <0.05 with the dependent variable. Result: A total of 74 (34.3%) neonates were admitted with neonatal sepsis. A surgical procedure is done before sepsis (AOR=2.9, 95% of CI(1.5 to5.6), last pregnancy wanted (AOR=2.8, 95% of CI(1.0 to 7.3), more frequent per-vaginal examination (AOR=2.6, 95% of CI (1.3 to 5.3), educational level unable to read and write(AOR=5.4, 95% of CI(1.0 to 27.7), low birth weight (AOR=5.4, 95% of CI(3.0 to 9.8), and getting care from unskilled health workers(AOR=2.7, 95% of CI(1.5 to 4.9) were significantly associated with neonatal sepsis at multivariable with less than 0.05 p values. Conclusion: This study indicated that the prevalence of neonatal sepsis was still high. Thus, immediate action should be taken before it leads to neonatal mortality and further complications. The study used only physician diagnosis to confirm neonatal sepsis, which may affect its prevalence and needs further investigation.
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