N N Poleshchuk, S P Kapitulets, Iu G Il'kevich, Z B Kvacheva
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[The use of electron microscopy for diagnosing spongiform encephalopathies].
The authors suggest an unsophisticated approach to laboratory diagnosis of spongiform encephalopathies induced by unconventional prion viruses, consisting in electron microscopic detection of abnormal helical Scrapie-associated fibrils. These fibrils are detectable in human and animal brain tissue samples and in cell cultures.
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