P.G. Newrick , C. Bowman , D. Green , I.A.D. O'Brien , S.R. Porter , C. Scully , R.J.M. Corrall
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Parotid salivary secretion in diabetic autonomic neuropathy
Parotid salivary flow rates and amylase concentrations were measured in three groups of eight subjects each (normal control, non-neuropathic diabetic, and neuropathic diabetic). Flow rates were significantly reduced in neuropathic diabetic patients as compared with normal controls (p < 0.001) and non-neuropathic diabetic patients (p < 0.02). Amylase concentrations were similar. These data are consistent with parasympathetic denervation of the parotid gland in diabetic neuropathy and provide evidence for a widespread distribution of autonomic denervation in diabetes.
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