脑内毛细血管灌注动态。

Blood vessels Pub Date : 1991-01-01 DOI:10.1159/000158861
U Göbel, H Theilen, H Schröck, W Kuschinsky
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引用次数: 11

摘要

本研究探讨了清醒大鼠脑内毛细血管的募集和储备问题。静脉注射球蛋白偶联异硫氰酸荧光素(FITC)标记灌注毛细血管,放射自显像测量脑血流。在高碳酸血症期间,灌注毛细血管密度与正常碳酸血症相比没有变化,尽管血流量明显增加。这表明在高碳酸血症期间,大脑中毛细血管募集不足。在对形态学上存在的毛细血管和灌注的毛细血管进行荧光染色的其他研究中,发现在正常、正常的条件下,所有毛细血管都有灌注。这些实验表明,大鼠脑中没有任何毛细血管储备。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Dynamics of capillary perfusion in the brain.

The present study investigates the question of capillary recruitment and reserve capillaries in the brains of awake rats. Perfused capillaries were marked by intravenous globulin-coupled fluorescein isothiocyanate (FITC) and cerebral blood flow was measured autoradiographically. During hypercapnia, the density of perfused capillaries was unchanged compared to normocapnia, although blood flow was markedly increased. This shows the lack of capillary recruitment in the brain during the high flow that occurs during hypercapnia. In additional studies using fluorescent staining both of morphologically existing and of perfused capillaries, perfusion of all capillaries during normal, normocapnic conditions was found. These experiments show the lack of any capillary reserve in the rat brain.

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