利用漫反射和定量荧光光谱测量卟啉纳米颗粒的体内解离动力学

Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN) Pub Date : 1900-01-01 DOI:10.1364/omp.2023.ow1e.6

Theo Husby, M. Valic, Y. Hiraishi, Nicholas Bernards, F. Yokote, Juan Chen, G. Zheng, K. Yasufuku, Brian Wilson, R. Weersink

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引用次数: 0

摘要

一种用于测量卟啉体治疗性纳米颗粒完整和解离状态浓度的漫反射和定量荧光光谱组合系统，与临床前离体PET测量和体内解离动力学进行了比较。

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Measuring in vivo Dissociation Kinetics of Porphysome Nanoparticles Using Diffuse Reflectance and Quantitative Fluorescence Spectroscopy

A combination diffuse reflectance and quantitative fluorescence spectroscopy system developed for measuring concentrations of intact and dissociated states of porphysome theranostic nanoparticles is compared to pre-clinical ex vivo PET measurements and in vivo dissociation kinetics.

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来源期刊

Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)

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