基于深度学习的脊柱侧凸自动诊断与测量系统

Zhiqiang Tan, Kai Yang, Yu Sun, Bo Wu, Huiren Tao, Ying Hu, Jianwei Zhang
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引用次数: 7

摘要

青少年特发性脊柱侧凸(idiopathic scoliosis, AIS)是一种三维脊柱结构畸形,影响1-4%的青少年,不仅导致外观变形,而且导致精神状态、肺功能、运动功能和生活质量受损。目前,AIS的诊断依赖于脊柱x线片上Cobb角的测量,由医生手动完成。这种方法存在观察者内部和观察者之间的变异,导致诊断错误。本研究旨在设计一种基于深度学习的脊柱侧凸自动诊断测量系统,以提高测量精度,辅助医生诊断。采用U-net分割网络对脊柱x线片进行分割。基于分割后的图像,采用最小外包络矩形和最小二乘法识别上、下端椎骨(UEV和LEV)的具体位置及其端板的斜率。随后,测量Cobb角为uv上终板与lev下终板之间的夹角。将人工测量的科布角与计算机测量的科布角进行比较,结果表明,计算机测量的科布角与人工测量的科布角相似。综上所述,该科布角自动测量系统可以辅助医生进行临床诊断。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
An Automatic Scoliosis Diagnosis and Measurement System Based on Deep Learning
Adolescent idiopathic scoliosis (AIS) is a three-dimensional structural deformity of the spine which affects 1–4% of adolescents and causes not only deformed appearance but also compromised mental status, pulmonary function, motor function and life quality. Currently, the diagnosis of AIS depends on the measurement of Cobb angle on spine radiographs, which is performed manually by doctors. Intra-observer and inter-observer variation exist in such method and causes errors in diagnosis. The purpose of this study is to design an automatic scoliosis diagnosis and measurement system based on deep learning to improve measurement accuracy and assist doctors in diagnosis. U-net segmentation network was used to segment the spine radiographs. Based on the segmented images, specific positions of upper and lower end vertebrae (UEV and LEV) and slopes of their endplates were identified by minimum outer envelope rectangle and least square method. Subsequently, Cobb angles were measured as angles between superior endplates of UEVs and inferior endplates of LEVs. After comparing manually measured Cobb angles with computer- measured Cobb angles, the result showed that the computer- measured Cobb angles were similar to the manually measured ones. To sum up, this system for automatic measurement of Cobb angle can assist doctors in clinical diagnosis.
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