利用深度学习预测g蛋白偶联受体:综述

Anuj Singh, A. Tiwari
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引用次数: 0

摘要

膜蛋白中最大的超级类是g蛋白偶联受体和gpcr,对药物设计目标非常重要。gpcr有时被称为七螺旋受体和七跨膜受体。gpcr负责多种物理化学和生物活动,如细胞生长、神经传递、嗅觉和视觉。本文综述了目前预测gpcr的相关方法。对gpcr的广泛研究已经取得了新的发现,为未被发现和有前途的药物设计提供了机会,并提供了有效的药物靶向g蛋白偶联受体治疗。本文主要关注深度学习的过程
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Prediction of G-protein Coupled Receptors using Deep Learning: A Review
The biggest super classes of the membrane proteins are G-protein coupled receptors as well as GPCRs are very significant for drug design goals. GPCRs are sometimes known as heptahelical receptor as well as seven-transmembrane receptor. GPCRs are accountable for several physicochemical and biological activities like cellular growth, neurotransmission, smell as well as vision. This paper presents a review related to current approaches to predict GPCRs. Extensive research on GPCRs have progressed to novel discoveries that open undiscovered and promising drug design opportunities and efficient drug-targeting Gprotein coupled receptors therapies. This paper concentrates primarily on the process of deep learning to
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