{"title":"移植免疫学","authors":"Shyamasree Ghosh","doi":"10.1201/9781351025546-7","DOIUrl":null,"url":null,"abstract":"The potential for stem cells to replace or restore tissues lost to injury or disease represents one of the most promising outcomes of regenerative medicine. However, immune rejection of stem cell grafts remains a challenge to clinical translation of stem cell research. Methods to overcome immune rejection of stem cell derived grafts must therefore be developed to fully realize the benefits of stem cell therapies. The purpose of the CIRM Stem Cell Transplantation Immunology Awards is to fund transformative research leading to the development of immune tolerance of pluripotent stem cell derivatives and potential correction of autoimmunity.","PeriodicalId":129878,"journal":{"name":"Computational Immunology","volume":"134 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2019-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Transplantation Immunology\",\"authors\":\"Shyamasree Ghosh\",\"doi\":\"10.1201/9781351025546-7\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The potential for stem cells to replace or restore tissues lost to injury or disease represents one of the most promising outcomes of regenerative medicine. However, immune rejection of stem cell grafts remains a challenge to clinical translation of stem cell research. Methods to overcome immune rejection of stem cell derived grafts must therefore be developed to fully realize the benefits of stem cell therapies. The purpose of the CIRM Stem Cell Transplantation Immunology Awards is to fund transformative research leading to the development of immune tolerance of pluripotent stem cell derivatives and potential correction of autoimmunity.\",\"PeriodicalId\":129878,\"journal\":{\"name\":\"Computational Immunology\",\"volume\":\"134 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-10-14\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Computational Immunology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1201/9781351025546-7\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Computational Immunology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1201/9781351025546-7","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
The potential for stem cells to replace or restore tissues lost to injury or disease represents one of the most promising outcomes of regenerative medicine. However, immune rejection of stem cell grafts remains a challenge to clinical translation of stem cell research. Methods to overcome immune rejection of stem cell derived grafts must therefore be developed to fully realize the benefits of stem cell therapies. The purpose of the CIRM Stem Cell Transplantation Immunology Awards is to fund transformative research leading to the development of immune tolerance of pluripotent stem cell derivatives and potential correction of autoimmunity.
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