{"title":"Prions","authors":"A. Sakudo","doi":"10.1201/b22030-14","DOIUrl":null,"url":null,"abstract":"Prions are infectious agents that long defied some of our basic ideas of biology. They appear to behave like other infectious organisms, yet they lack any of the most fundamental features of organisms. In particular, they lack any genetic material (DNA or RNA). Over time, work on prions has suggested that the \"infectious agent\" is actually a misfolded protein -which causes a normal cellular protein to change its shape to the misfolded form.","PeriodicalId":426583,"journal":{"name":"Handbook of Foodborne Diseases","volume":"1 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2018-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Handbook of Foodborne Diseases","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1201/b22030-14","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Prions are infectious agents that long defied some of our basic ideas of biology. They appear to behave like other infectious organisms, yet they lack any of the most fundamental features of organisms. In particular, they lack any genetic material (DNA or RNA). Over time, work on prions has suggested that the "infectious agent" is actually a misfolded protein -which causes a normal cellular protein to change its shape to the misfolded form.
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