一个高患病率国家的观点:马拉维。

D S Nyangulu
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引用次数: 0

摘要

1984年世界卫生组织开始提供援助时,国家结核病规划对痰检阳性病例改用短期化疗。经治疗后,痰检阳性病例的治愈率从50-55%提高到新发病例的87%(再治疗病例的治愈率为89%)。减少结核病问题的希望当时受到了与艾滋病毒有关的结核病病例的挑战,这些病例现在大大超出了服务范围。涂片阴性病例和肺外结核现在几乎占所有患者的三分之二。对他们来说,标准化疗现在已经改为2 R3H3Z3/2 HE(或TH)/4H,以尽量节省注射器、针头和注射用水的费用,并防止通过注射传播艾滋病毒。这一方案还将使该方案不需要住院治疗,因为病人将在流动的基础上服药。它还可能给地区结核病官员更多的时间来监督保健中心。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The point of view of a high prevalence country: Malawi.

The National Tuberculosis Programme switched to short-course chemotherapy for smear-positive cases when the IUATLD started to assist in 1984. Treatment results in smear-positive cases improved from a 50-55% cure rate to an 87% cure rate in new cases (and 89% in retreatment cases). The hope of reducing the tuberculosis problem was then challenged by the occurrence of HIV-related cases of tuberculosis which are now considerably over-stretching services. Smear-negative cases and extrapulmonary tuberculosis now represent almost two thirds of all patients. For them, standard chemotherapy has now been changed to 2 R3H3Z3/2 HE(or TH)/4H in order to try and save money on syringes, needles and water for injection as well as prevent transmission of HIV through injections. This regimen will also enable the programme to depart from hospitalization since patients will take medication on an ambulatory basis. It may also give more time to district tuberculosis officers for the supervision of health centers.

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