社会人口学因素对抑郁症管理的影响

J.W. Edefo, W. Udezi
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引用次数: 0

摘要

目的:探讨社会人口学因素对抑郁症患者抗抑郁药物治疗有效率的影响。方法:采用前瞻性研究设计,每位患者首次接触后随访6次。每4周对完成研究的患者进行随访,直至第24周。抑郁程度采用国际疾病分类-10标准确定,而抑郁严重程度采用医院焦虑和抑郁量表-抑郁(HADS-D)工具评估。结果(无抑郁)在初次接触时和每次随访时使用HADS-D评分进行测量。采用卡方分析和方差分析。结果:112例患者中有51例(46%)完成了研究,因此样本量为51例。女性占样本的65%(33)。与研究开始时相比,那些至少获得中等教育水平和个人收入的人的HADS-D分数下降的P < 0.05,而性别和所有年龄组的HADS-D分数下降的P也与研究最后一次随访时相似< 0.05。结论:受教育程度和个人收入对抗抑郁药物的应答率有影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The effects of sociodemographic factors on depression management
Objective: To explore the effect of sociodemographic factors on response rate to antidepressants therapy in depression management. Methods: A prospective study design of 6 follow-ups per patient after the initial contact was employed. Follow-up was done every 4 weeks for up to the 24 th week per patient that completed the study. Degree of depression was determined using the International Classification of Disease-10 criteria, whereas severity of depression was assessed using Hospital Anxiety and Depression Scale-depression (HADS-D) instrument. Outcome (depression-free) was measured at initial contact and also for each follow-up using HADS-D score. Chi-square and analysis of variance were used. Results: Fifty-one respondents out of 112 patients (46%) completed the study, and hence the sample size was 51 respondents. Females accounted for 65% (33) of the sample. Those who attained at least secondary level of education, and personal income as gave a P < 0.05 with regard to decrease HADS-D scores compare to when the study started, whereas the decrease HADS-D scores of sex and all age groups also gave a similar P < 0.05 as at the last follow-up of the study. Conclusion: Education status and personal income appear to affect the rate of response to antidepressant medications.
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