Construction of Evidence to Clarify the Importance of Dietary Management for Prevention of Cerebral Cardiovascular Disease: Relationship between Fish Intake and Cardio-metabolic Risk –and Study Design and Rationale

The background for this study is as follows: 1) A negative correlation has been found between fish intake and the onset of myocardial infarction. 2) Effects of fish consumption on the cardio-metabolic risk factors (cardio-metabolic risk: atherosclerosis-inducing risk factors caused by visceral obesity, such as hypertension, dyslipidemia, abnormal glucose tolerance, and metabolic syndrome) remain largely unknown. 3) It has been suggested that dietary fish consumption may be associated with improvement of the overall lifestyle and reduction of the cardio-metabolic risk. Based on this background, we attempted to reveal the effects of fish intake on the cardio-metabolic