预防中风前后痴呆

A. Fătu, A. Pâslaru, C. Stefanescu, I. Chiscop, Ș. Moisă, C. Dinu, V. Creangă-Zărnescu, M. Matei, Gabriela Bălan, A. Ciubară
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摘要

导读:痴呆症是一个重要的公共卫生问题,是唯一无法治疗或治愈的死亡原因。据世界卫生组织称,被诊断患有痴呆症的人数正在增加,2021年患者超过5500万(约占世界人口的5%),每3秒钟就有一个新病例被诊断出来。在中风之前和之后,痴呆症的患病率都在增加。目的:本文的目的是强调早期识别与认知能力下降相关的危险因素的重要性以及复杂的医疗保健方法的作用。方法:回顾性研究分析了2021年7月至12月住院的60例脑卒中和认知障碍患者的病历。此外,我们检索了最新的PubMed数据库和Cochrane图书馆关于这两种病理的共同危险因素。结果显示,更多的妇女受到这种使人衰弱的疾病的影响,其中72%的人年龄超过80岁。确定了以下可改变的危险因素:63%的患者患有高血压,42%患有复发性卒中,37%患有心房颤动,26%患有II型糖尿病,22%患有血脂异常,10%患有肥胖症。据信,三分之一的病例可以通过早期识别危险因素,特别是心血管因素,以及提高中风后的恢复效率来预防。这可以在疾病发作之前完成,促进精神和情绪健康,特别是认知能力,包括执行功能和容易发生神经退行性疾病或脑血管病变的人的记忆。在老年受试者中,健康的饮食、适度的体育活动、慢性减压、社会交往以及心血管危险因素的改善,可以被认为是防止痴呆症发生和发展的第一道防线。结论:病理过程早在临床表现出来之前就开始了,从而为识别或对抗疾病的前驱阶段提供了机会。我们推荐多因素干预来预防认知障碍和痴呆。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
THE PREVENTION OF DEMENTIA BEFORE AND AFTER STROKE
Introduction: Dementia is an important public health problem, the only cause of death that can not be treated or cured. The number of people who are diagnosed with dementia is increasing, over 55 million patients in 2021(about 5% of the world population), more than that a new case is diagnosed every 3 seconds, according World Health Organization. Prevalence of dementia is increasing, both before and after stroke. Aim: The purpose of this paper is to emphasize the importance of early identification of the risk factors associated with cognitive decline and the role of the complex health care approach. Method: The retroactive study involved analyzing the medical record of 60 subjects with stroke and cognitive impairments, hospitalized between july -december 2021. Furthermore we searched the latest PubMed database and Cochrane Library regarding the risk factors common for this two pathologies. The outcome showed that more women are affected by this debilitating disease, of which 72% were over 80 years old. The following modifiable risk factors were identified: 63% of patients had hypertension, 42% had recurrent stroke, 37% atrial fibrillation, 26% type II diabetes, 22% dyslipidemia, and 10% obesity. It is believed that one third of cases can be prevented by early identification of risk factors, especially cardiovascular, and by increasing the efficiency recovery after stroke. This can be done before the onset of the disease, growing the mental and emotional health, specificaly the cognitive abilitiy, including the executive function and the memory of people prone to neurodegeneration or cerebrovascular lesions. In elderly subjects, healthy diet, moderate physical activity, chronic stress reduction, social interaction along with improvement in cardiovascular risk factors, could be considered the first line of defense against the development and progression of dementia. Conclusions: The pathological process begins long before it manifests itself clinically, thus providing the opportunity to identify or combat the prodromal stages of the disease forward. We recommend multifactorial intervention to prevent cognitive impairment and dementia.
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